This study aimed at examining general trends of day-care center teachers in their teacher-infant interactions, job stress, and job-satisfaction, and analyzing the relative effects that the teachers\' general background variables have on the teacher-infant interactions. For these purposes, 136 teachers working at 25 day-care centers in Gwangju Metropolitan City were selected as the research subjects. Statistical analysis were conducted using SPSSWIN(12.0) for Cronbach’s alpha, average and standard deviations, Pearson’s correlation, regression analysis. The major findings are as follow; 1. the subjects were shown to perceive their teacher-infant interactions to be occurring well. Job stress was shown to have an overall average that was slightly lower than the median score and job-satisfaction resulted in an overall average being higher than the median score. 2. the variable that best explained the ‘overall teacher-infant interactions’ was job-satisfaction. The variable that best explains ‘care for physiological activities’, ‘positive interaction with the infants’, ‘encouragement of interaction among infants’ - one of the subfactors of teacher-infant interactions - was shown to be the job- satisfaction variable.