Objectives: The purpose of this study is to report the effectiveness of Korean medicine treatment on 254 patients visited obesity clinic. Methods: Two hundred fifty-four patients, who had visited obesity clinic from May 2013 to November 2014, were analyzed by bioelectrical impedance analysis. We analyzed changes of weight, skeletal muscle mass, fat mass, body mass index (BMI) and body fat percentage after treatment, also investigated differences of weight and fat mass loss according to age, BMI and body fat percentage. Results and Conclusions: Male and female percent of the study group was 3.5% and 96.5%. All patients were constituted with 50.0% of 20∼29-year-old group, 34.1% of 30∼39-year-old and 15.9% of 40 and more year-old. In BMI, 21kg/m2, 21.0∼22.9 kg/m2, 23.0∼29.9 kg/m2, above 30 kg/m2 were 20.5%, 30.3%, 42.1%, 7.1%, respectively. In Body fat percentage, under 25%, 25.0%∼29.9%, 30.0%∼34.9%, above 35% were 11.4%, 23.2%, 30.7%, 34.6%, respectively. 96.1% of patients were showed weight loss compared with baseline, the decrease of body weight was 2.96±1.86 kg, that of BMI was 1.13±0.70 kg/m2 and that of body fat percentage was 2.43%±2.06% after 1 month treatment. We observed a decline of weight and fat mass with higher BMI and body fat percentage at the baseline.