This study was designed to confirm the ethnic and socioeconomic differences in the obesity of Uzbekistan. Methods From 139 patients, visited Korean-Uzbekistan friendship hospital of Korean Medicine, gathered the information of the sex, height, weight, ethnic group, economic status, education level, self-desired weight, self-perception of weight status and experiences of weight reduction. Also patients completed the 10 questions about the association between obesity and disease. Results Koreans in Uzbekistan showed a significant lower value of body mass index (BMI) and a significant higher understanding between obesity and disease than other ethics. Socioeconomic differences in the obesity were not confirmed. People of Uzbekistan showed a little experience of weight reduction. Conclusions Koreans in Uzbekistan have a different prevalence and perception of the obesity with other ethnics. Researches about the relationship between obesity and metabolic factors, and prevention programs for obesity and metabolic syndrome are needed for the public health of Uzbekistan.