Objective: This study was to examined the mediating effect of active emotion regulation and marital quality in the relationships between self-compassion and maternal-fetal attachment. Methods: A questionnaire was administered to 836 pregnant women and the data were analyzed by SPSS21 and M-plus7, and statistical analysis, frequency analysis, and then structural equation modeling were performed. Results: First, self-compassion directly affects maternal-fetal attachment. Second, self-compassion was indirectly influenced by maternal-fetal attachment through active emotional regulation. Third, self-compassion indirectly affects maternal-fetal attachment through marital quality. Fourth, in regards to the relationship between self-compassion and maternal-fetal attachment, active emotional regulation and marital quality were mediated. Conclusion/Implications: we discussed implications for enhancing self-compassion and active emotional regulation and enhancing marital quality to increase the maternal-fetal attachment of pregnant women.