In order to support healthy college life for students with disabilities, it is necessary to provide individual support considering the characteristics of disabilities and the situation of students. The purpose of this study was to examine the effects of resilience enhancement program using social problem solving strategy on the resilience, stress, and psychological well-being of the college students with sensory disabilities. Four freshmen with sensory disabilities belonged to K university located in Gyonggi-do participated on the resilience intervention including 10 sessions and were conducted resilience, stress, psychological well-being test and in-dept interview. The results of this study showed that the resilience enhancement program using social problem solving strategy positively influenced on improving of stress, psychological well-being of the college students with disabilities. This study can be used as the basic data for the improvement of adaptation ability of college students with sensory disabilities in the future.