The purpose of this study was to investigate the relation between components of population, maternal health, need for health care, maternal lifestyle and environment from a conceptual model for cerebral palsy, and the occurrence of cerebral palsy with spastic quadriplegic. This study was a case-control design. The subjects consisted of 53 children with quadriplegic cerebral palsy as a case who were receiving treatment after a diagnosis for cerebral palsy at 3 university hospitals and 3 rehabilitation facilities, and 186 children as a control who were visiting well baby clinics and pediatric departments after screening at the same hospitals in Seoul. The data were collected by a structured questionnaire survey from October, 1998 to February, 1999. The odds ratios of risk factor was produced by χ2 and simple logistic analysiss. The unconditional logistic analysis was done by modeling the data, after adjusting for gestational age. Statistically associated with an increase the risks for spastic quadriplegia were asphyxia(OR=221.89, 95% CI 15.8-999.0) and maternal history of admission during the pregnancy (OR=10.55, 95% CI 2.2-50.4). The result suggested that the improvement of obstetric and neonatal care is necessary to prevent cerebral palsy with spastic quadriplegia.