The purpose of this study was to review the relationship between creativity and psychopathology. The relationship between creativity and psychopathology has been debated for literally hundreds of years. The relationship between creativity and psychopathology has been a source of speculation for centuries, dating back at least as far as Aristotle who suggested that all of the eminent writers and philosophers of his time suffered from melancholia. Henceforth, many studies have focused on the relationship among creativity, mood disorders, depression, bipolar disorder, suicide, short life-span, and schizophrenia. Creative individuals often are viewed as more eccentric than typical, and many of the common disturbances. And, many famous creators have suffered from mental disorder of various sorts. In conclusion, there is the dynamic interaction between creativity and psychopathology. In previous studies, however, some groups of artists were included. So there are limits to the generalization of the results. Key words: creativity, psychopathology, schizophrenia, affective disorder, depression, bipolar disorder