Objective : The purpose of this study was to investigate the effect of multimodal intervention, consisting ofphysical activities, cognitive training, and social interaction activities, on the quality of life, depression level, andcognitive function in elderly people with dementia. Methods : We used a single group pre- and post-test design. We executed a multimodal intervention for 10sessions The subjects included six elderly people with dementia who underwent eight 120 min. interventionsessions once a week. In the first and tenth sessions, the patients underwent pre- and post- tests. We usedGQOL, GDS-K, and MMSE-K as dependent measurements. Results : The GQOL score of the subjects was significantly increased (p<.05). The GDS-K scores decreased butnot significantly. The MMSE-K scores increased but not at a statistically significant rate (p>.05). There were nosignificant differences between mild dementia and moderate dementia in terms of the GQOL, GDS-K, andMMSE-K score variations (p>.05). Conclusion : Multimodal intervention is effective on the QoL of elderly people with dementia, and has positiveeffects on the depression level and cognitive function. Therefore, we provided evidence for occupational therapiststo provide professional and systemic intervention for elderly people with dementia.