The purpose of this study was to investigate the relationship between the coming out of female sexual minority, unconditional self-acceptance, social support, and psychosocial adjustment, and it was verified by setting unconditional self-acceptance and social support as the moderating variables in the relationship between coming out and psychological adjustment. To do this, we conducted to sexual minority over 18 years a questionnaire survey using the coming out scale, satisfaction with life scale, psychological well-being scale, the center for epidemiological studies depression scale, unconditional self-acceptance and the social support scale. Participants were fully briefed on the questionnaire and the survey was conducted after obtaining consent from the participants. Of the 215 questionnaires, 151 were used as the analysis data for this study, except for those who did not recognize themselves as sexual minorities, did not complete the questionnaire, or were male or female. Analysis was conducted by utilizing SPSS 20.0, the main results are as follows: First, there was a significant positive correlation between coming out and psychosocial adjustment. In other words, satisfaction with life and psychological well-being increases as much to coming out and depression have been shown to decrease. Second, unconditional self-acceptance did not control the effects of exposure on psychosocial adjustment. Third, social support has been shown to control the effects of coming out on psychosocial adjustment. In other words, the group with higher social support than the group with lower social support showed more psychological and social adjustment with more coming out. In particular, coming-out to friends of sexual minorities is more significant. Based on the results of this study, we aim to contribute to the understanding of gender minority and to utilize it in domestic gender minor counseling.