The purpose of this study was to analyze the factors influencing students’ selection of multiple majors and their college life experience. For this study, Graduates Occupational Mobility Survey (GOMS) 2019 data were the main source of data. The results are as follows. Over the past decade, it was found that 20% of four-year college students had chosen multiple majors. The ratios of students with multiple majors were the highest in the humanities, social sciences, and natural sciences in that order, while the most popular fields for multiple majors were business, the humanities, social sciences, and engineering in that order. The preference for majoring in engineering has increased compared to 10 years ago, while the preference for business majors has consistently been the highest. The rate of selection of multiple majors was significantly higher among female students attending universities in Seoul. Humanities students were more likely to choose multiple majors than those in other colleges. Students who responded that, if they had to do it over again, they would not have chosen their major were more likely to prefer multiple majors. Also, the higher their parents educational background, the more likely they were to choose multiple majors. In terms of the university life of students with multiple majors, they had a higher rate of enrollment for extra semesters, a higher grade point average (GPA), higher satisfaction with their universities, and greater participation in university programs. Students with multiple majors had a high rate of covering tuition with scholarships and a low amount of student loans. Based on the results of the above analysis, the implications of this study are that it provided basic data to understand students completing multiple majors, a phenomenon that has been increasingly emphasized in universities as part of university innovation in recent years.