This study examines the symbolic meanings of the cross in children’s cases of sandplay therapy with the consideration of a myth and the meanings of before and after Christianity. For this, when and how the cross appears, what meanings of the cross exist, and how therapy is processed with the cross, are explored. The cross exists from prehistoric times and means life energy, life power, eternal life, and change through initiation. As a myth, the cross means sacrifice, death, rebirth, and wisdom. In pre-Christian times, the cross means unification, synthesis, harmony, victory, life, fullness, and integrity. In Christian times, the cross means redemption through death, hope, victory, and resurrection. The cross can appear in any phase during therapy by making the cross with sand or using cross figures. In terms of the symbolic meanings of the cross, four children seem to gain spiritual energy for encouragement and guidance, the expression of despair by burying the cross, which means hope, seeking balance in internal world, and praying for redemption similar to meanings in a myth and before and after Christianity. The cross appearing in sandboxes seems to be very functional and meaningful through the process of therapy. Practical issues in sandplay therapy are suggested.