The purpose of this present study is to examine the relationship among Career Decision-Making Level, Career Decision-Making Self Efficacy, Career Barrier, Career Attitude Maturity, and Spiritual Well-being among Korean College Students. The correlations among Career Decision-Making Self Efficacy, Career Barrier, Career Attitude Maturity, and Spiritual Well-being were analyzed and gender differences of each variable were studied. This study is aiming to support career development and provide foundational resources for career guidance by suggesting selective diagnosis and treatment according to career development of college students. The data was collected among 800 college students from H university located in P city, Korea. Tests of Career Decision-Making Level, Career Decision-Making Self Efficacy, Career Barrier, Career Attitude Maturity, and Spiritual Well-being were conducted among these subjects. The study examined the following hypotheses analyzing t-test, correlation, and regression by SPSS 15.00 program. Hypothesis1.There are gender differences in Career Decision-Making Self Efficacy, Career Barrier, Career Attitude Maturity, and Spiritual Wellbeing. Hupothesis2. Career Decision-Making Level and Career Barrier are negatively correlated. Hypothesis3.Career Decision-Making Level, Career Decision-Making Self Efficacy, Career Attitude Maturity, and Spiritual Well-being are positively correlated. The results are as follow: First, There are no gender differences in Career Decision-Making Level, Career Decision-Making Self Efficacy, Career Barrier, and Career Attitude Maturity while there is a gender difference in Spiritual Well-being. Second, Career Decision-Making Level and Career Decision-Making Self Efficacy are positively correlated whereas Career Barrier, Career Attitude Maturity, and Spiritual Well-beingare negatively correlated. It is reported that the results and hypothesis in Career Decision- Making Level, Career Decision-Making Self Efficacy and Career are consistent, while the results and hypothesis in Career Attitude Maturity and Spiritual Well-being are inconsistent. Findings of this study suggest that specialized program to develop students’self-efficacy and career attitude maturity by individualized counseling intervention is needed as well as support program to assist students to recognize less career barriers.