The purpose of this study is to understand the experiences of treating diseases of preschool childhood cancers and to study the systematic counseling care methodology. According to the study, the subject of play therapy for children suffering from childhood cancer during the preschool age, has six areas, including general theme of play therapy, medical play therapy topics, spiritual play therapy topics, and play course theme, system connected theme, a system for researchers. In terms of the results of the theme analysis and systematic perspective on the spirituality and culture of children, the main theme was analyzed as “a child still growing during the course of the treatment process.” Based on the analyzed findings, the researcher develops a systematic Christian (pastoral) counseling care model for children who experience chronic diseases such as childhood cancer and proposes a concrete practice in the treatment of Christian (pastoral) counseling medical play.