Purpose: The purpose of this study was to examine the effectiveness of Adult Daycare Service (ADS) based on partnership with caregivers for older adults who have had a stroke and their family caregivers. Methods: A quasi-experimental intervention study design was used. Older adults with a stroke from two ADS centers in Korea were assigned to either the experimental (n=16) or control group (n=13). The experimental group received health education and a tailored rehabilitation program by trained ADS center nurses for 12 weeks. Based on the concept of partnership family caregivers also participated in the intervention. Results: The mean ages of the elders were 76.6 years (experimental) and 77.0 years (control). There were no significant differences in socio-demographic and clinical characteristics between the two groups. Intervention participants showed improvement in diastolic blood pressure (p =.019), cognitive function (p<.001), instrumental activities of daily living (p<.001), and nutritional status (p<.001). Conclusion: Further research is needed to develop nursing interventions for older adults following a stroke, being treated in long term care facilities, as well as, at home and to evaluate long term effects of a partnership intervention to enhance participants adherence, health status, and the quality of life for older adults with stroke.