The purpose of this study to compare of clinical profile between obese and nonobese type 2 diabetic patients. The subjects were consist of 111 obese(50 male, 61 female) and 159 nonobese(79 male, 80 female) type 2 diabetic patients underwent fasting blood glucose, 2-hour postprandial blood glucose, HbA₁c, total cholesterol, triglyceride, high density lipoprotein, microalbuminuria, fasting C-peptide and 2-hour postprandial C-peptide were measured. Diabetes was diagnosed according to the American Diabetes Association(ADA)criteria. Obesity was defined as body mass index(BMI, kilograms per meters squared)≥23. Data analysis were t-test, chisquare test in SAS program. The results were as follows : 1) Triglycerides and 2-hour postprandial C-peptide were significant higher in obese than nonobese patients. 2) Systolic blood pressure, Diastolic blood pressure, fasting blood sugar, 2-hour postprandial blood glucose, HbA₁c, total cholesterol, high density lipoprotein, microalbuminuria and fasting C-peptide were no difference between obese and nonobese groups. These data indicate that obesity is a risk factor for the development of coronary heart disease(CHD) in diabetic patients. Therefore, weight reduction have beneficial effects on insulin action and glycemic control in obese type 2 diabetic patients.