대장내시경 피검진자의 대장용종 위험요인 분석

박복희; 이윤미

서지반출

국문초록

사회경제적 수준의 향상과 함께 의료기술의 발달로 예방의학 및 건강에 관한 관심이 높아지고 있어, 건강검진에 의해 발견되는 질병률이 증가하고 있다. 악성신생물에 의한 사망률은 인구 10만 명당 96.3명으로, 33.3명으로 2위인 뇌혈관 질환보다 높은 비율로 1위를 차지하고 있다(Korea National Statistical Office, 2012). 그 중 대장암은 우리나라에서 발생하는 매우 흔한 암으로 전체 암 발생 중 14.2%로 갑상샘암, 위암에 이어 3위이고, 대장암으로 인한 연도별 사망률은 계속 증가하고 있는 추세이다(Jung et al., 2013). 최근에 대장암의 발생기전은 대장선종에서 대장암으로 전환된다는 “선종-암종 전환”으로 생각되면서(Morimoto et al., 2002), 대장암 예방을 위해서 대장암 전구 병변인 대장용종을 조기 발견하는 것과 대장용종 발생에 영향을 줄 수 있는 생활 환경적 위험인자를 분석하는 데 관심이 증가하고 있다.

영문초록

Purpose: The purpose of this study was to identify the prevalence and risk factors of colon polyps. Methods: The subjects were 180 adults enrolled from examinees who underwent colonoscopy at the health promotion center and OPD in Ulsan University Hospital. The risk factors were collected by a self-reporting standardized questionnaire and medical records. Data analysis involved chi-square test, and multiple logistic regression. Results: The prevalence of colon polyps was 41.6%. The risk factors for colon polyps were significantly increased by the cases of subjects more than 50 years old (OR, 9.213; CI, 3.291-25.789), subjects who didn’t have any regular high-intensity exercise (OR, 4.762; CI, 1.387-16.351), subjects whose intake of fruits was less than once per a week (OR, 5.938; CI, 1.069-32.985) and subjects who showed irregular defecation (OR, 3.066; CI, 1.178-7.980). Conclusion: This study suggests that eating habits and proper exercise, which promote a normal habit of defecation so as to be helpful in preventing colon polyps.

키워드

Colonic polyps Risk factors 대장용종 위험요인

참고문헌 (30건)

Choe, S. E., & Lee, S. Y. (2011). Characteristics and risk factors on colorectal polyps by the gender in health screen examinees. Journal of Korean Biolology Nursing Science, 13(2), 164-173.
Dukas, L., Platz, E. A., Colditz, G. A., Willet, W. C., & Giovannucci, E. L. (2000). Bowel movement, use of laxatives and risk of colorectal adenomatous polyps among women (United States). Cancer Causes Control, 11(10), 907-914.
Erhardt, J. G., Kreichgauer, H. P., Meisner, C., Bode, J. C., & Bode, C. (2002). Alcohol, cigarette smoking, dietary factors and the risk of colorectal adenomas and hyperplastic polyps-a case control study. European Journal of Nutrition, 41(1), 35-43.
Frezza, E. E., Wachtel, M. S., & Chiriva-Internati, M. (2006). Influence of obesity on the risk of developing colon cancer. Gut, 55(2), 285-291.
Hassan, C., Pickhardt, P. J., Marmo, R., & Choi, J. R. (2010). Impact of lifestyle factors on colorectal polyp detection in the screening setting. Diseases of the Colon and Rectum, 53(9), 1328-1333. http://dx.doi.org/10.1007/DCR.0b013e3181e10daa
Jeon, S. H. (2000). Case-control study on colorectal polyps and smoking & other lifestyle factors in general health evaluations. Unpublished master’s thesis, Seoul National University, Seoul.
Jeong, S. Y. (2002). Korean national guidelines on screening and surveillance for early detection of colorectal cancers. Korean Journal of Gastrointestinal Endoscopy, 24(6), 317-320.
Ji, J. H., Park, B. J., Park Y. S., Hwang, J. H., Jeong, S. H., Kim, N. Y., et al. (2007). Clinicopathologic study of colorectal polyps and obesity in Korean adults. The Korean Journal of Gastroenterology, 49(1), 10-16.
Jung, Y. W., Won, Y. J., Kong, H. J., Oh, C. M., Seo, H. G., & Lee, J. S. (2013). Cancer statistics in Korea: incidence, mortality, survival and prevalence in 2010. Cancer Research and Treat, 45(1), 1-14.
Kim, C. S. (2010). The association of obesity and left colonic adenomatous polyps in Korean adult men -retrospective cohort study. Unpublished doctoral dissertation, Ulsan University, Ulsan.
Kim, M. C., Kim, C. S., & Jeong, T. H. (2005). The effect of physical activity on colorectal polyps. Korean Journal of Family Medicine, 26(7), 391-396.
Kim, M. C., Kim, C. S., Lee, D. K., & Jeong, T. H. (2008). The association between distal colon adenoma and the metabolic syndrome and lifestyle factors in male examinees in a university hospital. Korean Journal of Family Medicine, 29(3), 195-200.
Kim, M. C., Kim, D. H., & Jeong, T. H. (2002). Risk factors of colorectal polyps in Korean adults. Korean Journal of Family Medicine, 23(7), 890-896.
Kim, M. K., Lee, W. C., Choi, K. Y., Kim, S., Lee, S. Y., & Lee-Kim Y. J. (1998). A case-control study on dietary factors of colorectal adenomatous polyps by sites. Korean Journal of Epidemiology, 20(1), 154-166.
Korea National Statistical Office (2012). Statistics Korea; 2012 [cited 2013 Jan 4]. Available from: http://kostat.go.kr
Korean National Health and Nutrition Examination Survey [KNHANES] (2009). Korea national health & nutrition examination survey. Available from http://knhanes.cdc.go.kr
Larsen, I. K., Grotmol, T., Almendingen, K., & Hoff, G. (2006). Lifestyle as a predictor for colonic neoplasia in asymptomatic individuals. BMC Gastroenterology, 6(5), 1-12. http://dx.doi.org/10.1186/1471-230X-6-5
Lee, H. L., Son, B. K., Lee, O. Y., Jeon, Y. C., Han, D. S., Sohn, J. H., et al. (2007). Abdominal obesity, insulin resistance and the risk of colorectal adenoma. The Korean Journal of Gastroenterology, 49(3), 147-151.
Lee, H. M., Lee, S., Lim, J. K., Seo, J. W., Lee, K. S., Baek, S. C., et al. (2009). Relationship of colorectal polyps and the risk factors including obesity, age, alcohol and smoking. Chonnam Medical Journal, 45(3), 168-174. http://dx.doi.org/10.4068/cmj.
Lieberman, D. A., Prindiville, S., Weiss, D. G., & Willett, W. (2003). Risk factors for advanced colonic neoplasia and hyperplastic polyps in asymptomatic individuals. Journal of the American Medical Association, 290(22), 2959-2967.
Lipkin, M., Reddy, B., Newmak, H., & Lamprecht, S. A. (1999). Dietary factors in human colorectal cancer. Annual Review of Nutrition, 19, 545-586.
Morimoto, L. M., Newcomb, P. A., Ulrich, C. M., Bostick, R. M., Lais, C. J., & Potter, J. D. (2002). Risk factors for hyperplastic and adenomatous polyps: evidence for malignant potential? Cancer Epidemiology Biomarkers & Prevention, 11(10), 1012-1018.
Nam, J. H., & Yang, C. H. (2008). Clinical characteristics and risk factors of colon polyps in Gyeongju and Pohang area. The Korean Journal of Gastroenterology, 52(3), 142-149.
Oh, S. Y., Lee, J. H., & Kim, H. J. (2004). Analyses on the associations of dietary patterns with colon cancer risk. Korean Journal of Nutrition, 37(7), 550-556.
Park, J. H. (2008). Clinical characteristics and risk factors for colon polyp in the health screen examinee. Unpublished master’s thesis, Kyungpook National University, Daegu.
Park, J. K., Jang, S. K., & Min, S. (2002). Effects of stretching exercise on quality of like, depression, total cholesterol in the elderly. Journal of Korean Biological Nursing Science, 4(2), 139-150.
Rosenberg, L. Boggs, D., Wise, L. A., Palmer, J. R., Roltsch, M. H., Makambi, K. H., et al. (2006). Follow-up study of physical activity and incidence of colorectal polyps in African-American women. Cancer Epidemiology, Biomarkers & Prevention, 15(8), 1438
Sandhu, M. S., Dunger, D. B., & Giovannucci, E. L. (2002). Insulin, insulinlike growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer. Journal of the National Cancer Institute, 94(13), 972-980.
Song, H. S. (2009). The risk factors for colonic adenomatous polyps in health examinee. Unpublished master’s thesis, Kyungsang National University, Jinju.
Wang, Y. Y., Lin, S. Y., Lai, W. A., Liu, P. H., & Sheu, W. H. (2005). Association between adenomas of rectosigmoid colon and metabolic syndrome features in a Chinese population. Journal of Gastroenterology and Hepatology, 20(9), 1410-1415.

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