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151.

Transepithelial Transport of Organic Cation and Its Inhibition by Sulfhydryl and Carboxyl Reagents in Opossum Kidney Cell Monolayer

Woo, Jae-Suk, Oh, Se-Ok, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 6 53-62 (10 pages)

Woo, Jae-Suk, Oh, Se-Ok, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 저
...
- 3,000원
Transepithelial transport of tetraethylammonium (TEA) was studied in monolayers of opossum kidney cells cultured on permeable membrane filters. [14C]-TEA was transported across the OK cell monolayer from basolateral to apical side by a saturable process which can be stimulated by acidification of the apical medium. The apparent Michaelis-Menten constant (Km) and the maximum velocity(Vmax) for the transport were 41 μM and 147 pmole/ mg protein/ min, respectively. The transport was significantly...
152.

Properties of Single K+ Channels of Skeletal Muscle Incorporated into Planar Lipid Bilayer

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 2 13-28 (16 pages)

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 저
...
- 4,500원
single K+ channels of skeletal muscle from the rat and frog were into planar lipid bilayers and their properties were studied. Fusion was induced by an osmotic gradient. Of the four types of K+ channels recorded, the two most frequently observed were a voltage and Ca2+-activated K+ channel and a K+ channel with a prominent conductance substate. The first K+ channel was identified as the large Ca2+-activated K+ (BK) channel because the open-state probability was increased with depolarization...
153.

Rapid Measurement of NH3 and Weak Acid Permeation Through Liposomes and Renal Proximal Tubule Membranes

Bae, Hae-Rahn, Suh, Duck-Joon, Lee, Sang-Ho 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 11 203-214 (12 pages)

Bae, Hae-Rahn, Suh, Duck-Joon, Lee, Sang-Ho 저
...
- 4,100원
Using the methods of stopped-flow and epifluorescence microscopy with entrapped fluorophore, membrane permeability of NH3 and weak acids in liposomes, renal brush border (BBMV) and basolateral membrane vesicles (BLMV), and primary culture cells from renal proximal tubule was measured. Permeability coefficient (cm/sec) of NH3 was (2.9 X 10-2 in phosphatidylcholine liposome 25℃), 5.9 X 10-2 in renal proximal tubule cell (37℃), 4.0 X 10-2 and 2.4 X 10-2 in BBMV and BLMV (25℃), respectively....
154.

Role of Na+Ca2+ Exchange in the Control of Contractility in Rabbit Basilar Arterial Smooth Muscle

Kim Eui-Yong, Han Jin 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 6 159-168 (10 pages)

Kim Eui-Yong, Han Jin 저
...
- 3,000원
a function of changes in the Na+ electrochemical gradient in order to determine the contribution of Na+/Ca2+ exchange to the modulation of contractility. Ouabain (10-5 M) or K+-free Tyrode solution caused an increase in tonic tension even in the presence of a Ca2+ channel blocker (10-6 M verapamil) and an α-receptor blocker (10-5 M phentolamine). After treatment with ouabain (10-5 M), contractions were augmented by reduction of external Na+ concentration. The longer the treatment with ouabain...
155.

Role of Na+-K+ Pump on Endothelium-dependent Relaxation

Sung, Sang-Hyun, Roh, Joon-Ryang, Park, Tae-Sic, Suh, Suk-Hyo, Hwang, Sang-Ik, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 8 199-208 (10 pages)

Sung, Sang-Hyun, Roh, Joon-Ryang, Park, Tae-Sic, Suh, Suk-Hyo, Hwang, Sang-Ik, Kim, Ki-Whan 저
...
- 3,000원
To study the underlying mechanism through which the endothelium-dependent relaxation is inhibited by blocking the Na+ -K+ pump, the effects of Na+ -K+ pump blockade on the release of EDRF and its relaxing activity were examined, using organ bath study, bioassay technique, and cGMP measurement. Endothelium-dependent relaxation was attenuated by blocking the Na+ -K+ pump in the vascular ring with intact endothelium. In bioassay experiment EDRF release was decreased with the blockade of the Na+...
156.

Immunocytochemical Study on the Translocation Mechanism of Glucose Transporters by Insulin

Hah, Jong-Sik, Kim, Ku-Ja 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 2 123-138 (16 pages)

Hah, Jong-Sik, Kim, Ku-Ja 저
...
- 4,500원
The mechanism of insulin action to increase glucose transport is attributed to glucose transporter translocation from intracellular storage pools to the plasma membrane in insulin-sensitive cells. The present study was designed to visualize the redistribution of the glucose transporter by means of an immunogold labelling method. Our data clearly show that glucose transporter molecules were visible by this method. According to the method this distribution of glucose transporters between cell...
157.

Effects of Cd2+ on the Contractility in the Antral Circular Muscle of Guinea-pig Stomach

Kim, Eui-Yong, Han, Jin 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 2호 4 129-136 (8 pages)

Kim, Eui-Yong, Han, Jin 저
...
- 3,000원
The effects of Cd2+ on spontaneous contraction, and the contractures induced by 0mM Na+, 60mM K+ and 10-6 M acetylcholine, 1mM caffeine were studied in order to elucidate diverse actions of Cd2+ on the Ca2+ mobilization related with contractility in the antral circular muscle of guinea pig stomach. Cd2+ inhibited the spontaneous contraction in a does dependent manner (10-6 M 10-4 M). Cd2+ (3 X 10-5M) suppressed 60 mM K+ induced contracture composed or a phasic and a tonic response and the...
158.

Effect of Various Divalent Ions on the Calcium Current of Adrenal Medullary Chromaffin Cells in the Rat

Kim, Jun, Leem, Chae-Hun, Kim, Sang-Jeong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 2호 2 113-122 (10 pages)

Kim, Jun, Leem, Chae-Hun, Kim, Sang-Jeong 저
...
- 3,000원
It is well known that chromaffin cells of adrenal medulla secrete catecholamine in response to sympathetic nerve activation and the influx of Ca2+ through the voltage dependent Ca2+ channels (VDCC) in the cell membrane do a major role in this secretory process. In this study, we explored the effect of divalent cations on VDCC of rat chromaffin cells. Rat (Sprague-Dawley rat, 150-250 gm) chromaffin cells were isolated and cultured. Standard giga seal, whole cell recording techniques were employed...
159.

A Study on the Na+/Ca2+ Exchange Mechanism in the Smooth Muscle of Guinea-pig Stomach

Kim, Eui-Yong, Han, Jin, Kim, Ki-Whan 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 1호 6 55-68 (14 pages)

Kim, Eui-Yong, Han, Jin, Kim, Ki-Whan 저
...
- 4,300원
The effects of changes in extracellular Na+ and Ca+ concentration on the membrane potential and contractility were studied in the antral circular muscle of guinea pig stomach in order to elucidate the existence and the nature of Na+/Ca2+ exchange mechanism. All experiments were performed in tris buffered Tyrode solution which was aerated with 100% O2 and kept at 35℃. The treatment of 10-5 ouabain was performed to induce intracellular Na+ loading prior to the start of experiment. The results...
160.

Ionic Dependence and Modulatory Factors of the Background Current Activated by Isoprenaline in Rabbit Ventricular Cells

Leem, Chae-Hun, Lee, Suk-Ho, So, In-Suk, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 1호 2 15-26 (12 pages)

Leem, Chae-Hun, Lee, Suk-Ho, So, In-Suk, Ho, Won-Kyung, Earm, Yung-E 저
...
- 4,100원
In order to elucidate the properties of the background current whole cell patch clamp studies were performed in rabbit ventricular cells. Ramp pulses of ±80 mV from holding potential of 40 mV(or 20 mV) at the speed of 0.8 V/sec were given every 30 sec(or 10 sec) and current-voltage diagrams(I-V curve) were obtained. For the activation of the background current isoprenaline, adenosine 3 ,5 -cyclic monophosphate(dBcAMP), guanosine 3 ,5 -cyclic monophosphate(cGMP), and N6-2 -o-dibutyryladenosine 3...

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