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Long-term Follow-up of Cutaneous Hypersensitivity in Rats with a Spinal Cord Contusion
Ji-InJung, JunesunKim, SeungKilHong, YoungWookYoon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.6 3 299-306 (8 pages)
Sometimes, spinal cord injury (SCI) results in various chronic neuropathic pain syndromes that occur diffusely below the level of the injury. It has been reported that behavioral signs of neuropathic pain are expressed in the animal models of contusive SCI. However, the observation period is relatively short considering the natural course of pain in human SCI patients. Therefore, this study was undertaken to examine the time course of mechanical and cold allodynia in the hindpaw after a spinal... -
Multiple 5-Hydroxytryptamine (5-HT) Receptors Are Involved in the Melittin-induced Nociceptive Responses in Rat I. Role of Peripheral 5-HT Receptor
HongKeeShin, SeoEunLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.5 9 221-226 (6 pages)
Melittin-induced tonic pain model is characterized by local inflammation, edema, spontaneous flinchings, and sustained mechanical hypersensitivity. These nociceptive responses are mediated through selective activation of capsaicin-sensitive primary afferent fibers by melittin. The present study was undertaken to elucidate the role of peripheral 5-hydroxytryptamine (5-HT) receptors in the melittin-induced nociceptive responses. Changes in mechanical threshold, flinching behaviors and paw... -
Melittin-induced Nociceptive Responses are Alleviated by Cyclooxygenase-1 Inhibitor
JoohyunKim, HongKeeShin, KyungHeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.1 8 45-50 (6 pages)
Melittin-induced pain model has been known to be very useful for the study of pain mechanism. Melittin-induced nociceptive responses are reported to be modulated by the changes in the activity of excitatory amino acid receptor, calcium channel, spinal serotonin receptor and extracellular signaling-regulated kinase. The present study was undertaken to investigate the role of cyclooxygenase (COX) in the melittin-induced nociception. Changes in mechanical threshold, flinchings and paw thickness... -
Calcium Modulates Excitatory Amino Acid (EAA)- and Substance P-induced Rat Dorsal Horn Cell Responses
HongKeeShin, SokHanKang, InDukChung, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 5 35-45 (11 pages)
Excitatory amino acid (EAA) and substance P (SP) have been known to be primary candidates for nociceptive neurotransmitter in the spinal cord, and calcium ions are implicated in processing of the sensory informations mediated by EAA and SP in the spinal cord. In this study, we examined how Ca2 modified the responses of dorsal horn neurons to single or combined iontophoretical application of EAA and SP in the rat. All the LT cells tested responded to kainate, whereas about 55% of low... -
抗憂戀劑 Iminodibenzyl derivatives 의 副作用 및 禁斷 症狀에 關하여
李吉弘, 趙容南 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 1970, 제 9권 제 2호 2 115-121 (7 pages)
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지역사회 통합 돌봄 대상자의 재활 서비스 이용에 따른 신체 능력의 차이
김미점 고령자치매작업치료학회 고령자·치매작업치료학회지 11 Pages
고령자치매작업치료학회 고령자·치매작업치료학회지 2022, 제 16권 제 1호 8 85-95 (11 pages)
목적: 본 연구는 청양군에 거주하고 있는 지역사회 통합 돌봄 서비스 대상자의 재활 서비스 이용 전후의신체 능력의 차이에 대해 알아보고자 한다. 연구방법: 본 연구는 충남 청양에 거주하는 지역사회 통합 돌봄 서비스 대상자 중 60세 이상의 노인 150명을대상으로 하였다. 자료 분석방법은 SPSS 23.0 프로그램을 이용하여 일반적 특성은 빈도분석, 신체 능력의 수준은 빈도 및 기술통계, 변인에 따른 신체 능력의 차이는 다변량 분석(MAVOVA)을 실시하였다. 연구결과: 지역사회 통합 돌봄 서비스 대상자의 재활 서비스 이용 전 후의...


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