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Cilostazol Attenuates 4-hydroxynonenal-enhanced CD36 Expression on Murine Macrophages via Inhibition of NADPH Oxidase-derived Reactive Oxygen Species Production
MiRanYun, HyeMiPark, KyoWonSeo, ChaeEunKim, JungWookYoon, ChiDaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 5 99-106 (8 pages)
In addition, HNE-enhanced expression of CD36 was reduced by these inhibitors, which indicated a role for NADPH oxidase and 5-LO on CD36 expression. In our present study, cilostazol was a significant inhibitor of ROS production, as well as CD36 expression induced by HNE. An increase in NADPH oxidase activity by HNE was significantly attenuated by cilostazol, however cilostazol had no effect on HNE-enhanced 5-LO activity. Together, these results suggest that cilostazol attenuates HNE-enhanced CD36... -
Hairy Root Cultures of Taxus cuspidata for Enhanced Production of Paclitaxel
Kim. Jung-A, Baek. Kwang-Hyun, Son. Young-Mi, Son. Sung-Ho, Shin. Heung-Sop 한국응용생명화학회 Journal of the Korean Society for Applied Biological Chemistry 7 Pages
한국응용생명화학회 Journal of the Korean Society for Applied Biological Chemistry 2009, Vol.52 No.2 144-150 (7 pages)
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Enhanced Production and Partial Purification of Glucoamylase from Mutated Bacillus sp. FME
Kumar. Gudi Satheesh, Chandra. Muni Ramanna Gari Subhosh, Sujana. Yakasiri Nagasai, Reddy. Bontha Rajasekhar, Choi. Yong-Lark 한국응용생명화학회 Journal of applied biological chemistry 7 Pages
한국응용생명화학회 Journal of applied biological chemistry 2009, Vol.52 No.5 412-418 (7 pages)
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High-throughput Screening Strategy Used for Enhanced Production of Pigment by Monascus purpureus D39-4
Tan. Jun, Chu. Ju, Shi. Wenjuan, Lin. Cheng, Guo. Yuanxin, Zhuang. Yingping, Zhang. Siliang, Imanaka. Tadayuki 한국식품과학회 Food science and biotechnology 8 Pages
한국식품과학회 Food science and biotechnology 2012, Vol.21 No.6 1603-1610 (8 pages)
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Microbial Levan from Pseudomonas fluorescens: Characterization and Medium Optimization for Enhanced Production
Jathore. Nagnath R., Bule. Mahesh V., Tilay. Ashwini V., Annapure. Uday S. 한국식품과학회 Food science and biotechnology 9 Pages
한국식품과학회 Food science and biotechnology 2012, Vol.21 No.4 1045-1053 (9 pages)
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Optimization of Fermentation Parameters for Enhanced Production of Naringinase by Soil Isolate Aspergillus niger VB07
VinothKumar. Vaidyanathan, RevathiBabu. Periasamy Kayambu Subash 한국식품과학회 Food science and biotechnology 3 Pages
한국식품과학회 Food science and biotechnology 2010, Vol.19 No.3 827-829 (3 pages)
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Statistical Optimization of Physical Parameters for Enhanced Bacteriocin Production by L. casei
Kumar. Mukesh, Jain. Alok Kumar, Ghosh. Moushumi, Ganguli. Abhijit 한국생물공학회 Biotechnology and bioprocess engineering 11 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2012, Vol.17 No.3 606-616 (11 pages)
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Enhanced Acetoin Production by Serratia marcescens H32 Using Statistical Optimization and a Two-stage Agitation Speed Control Strategy
Sun. Jianan, Zhang. Liaoyuan, Rao. Ben, Han. Yun-Bin, Chu. Ju, Zhu. Jiawen, Shen. Yaling, Wei. Dongzhi 한국생물공학회 Biotechnology and bioprocess engineering 8 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2012, Vol.17 No.3 598-605 (8 pages)
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Sequential Optimization Approach for Enhanced Production of Glutamic Acid from Corynebacterium glutamicum 2262 Using Date Juice
Abdenacer. Mouffok, Kahina. Bedaida Ibtissam, Aicha. Nancib, Nabil. Nancib, Jean-Louis. Goergen, Joseph. Boudrant 한국생물공학회 Biotechnology and bioprocess engineering 9 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2012, Vol.17 No.4 795-803 (9 pages)
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Enhanced Production of Heteropolysaccharide-7 by Beijerinckia indica HS-2001 in Repeated Batch Culture with Optimized Substitution of Culture Medium
Jin. Il-Hyuck, Jung. Dae-Young, Son. Chang-Woo, Kim. Sung-Koo, Gao. Wa, Chung. Chung-Han, Lee. Jin-Woo 한국생물공학회 Biotechnology and bioprocess engineering 11 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2011, Vol.16 No.2 245-255 (11 pages)
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Optimization of Media Components for Enhanced Arachidonic Acid Production by Mortierella alpina under Submerged Cultivation
Nisha. Alpettiyil, Rastogi. Navin Kumar, Venkateswaran. Govindarjulu 한국생물공학회 Biotechnology and bioprocess engineering 9 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2011, Vol.16 No.2 229-237 (9 pages)
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Enhanced Curdlan Production in Agrobacterium sp. ATCC 31749 by Addition of Low-polyphosphates
Yu. Lijun, Wu. Jianrong, Liu. Jia, Zhan. Xiaobei, Zheng. Zhiyong, Lin. Chi Chung 한국생물공학회 Biotechnology and bioprocess engineering 8 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2011, Vol.16 No.1 34-41 (8 pages)
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Optimization of Mineral Salts in Medium for Enhanced Production of Pullulan by Aureobasidium pullulans HP-2001 Using an Orthogonal Array Method
Gao. Wa, Kim. Yi-Joon, Chung. Chung-Han, Li. Jianhong, Lee. Jin-Woo 한국생물공학회 Biotechnology and bioprocess engineering 9 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2010, Vol.15 No.5 837-845 (9 pages)
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Enhanced Production of Human Epidermal Growth Factor under Control of the phoA Promoter by Acetate-tolerant Escherichia coli DB15 in a Chemically Defined Medium
Zhang. Yanjun, Li. Zhimin, Ye. Qin 한국생물공학회 Biotechnology and bioprocess engineering 9 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2010, Vol.15 No.4 626-634 (9 pages)
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Enhanced Continuous Production of Lovastatin Using Pellets and Siran Supported Growth of Aspergillus Terreus in an Airlift Reactor
Gupta. Kamakshi, Mishra. P.K., Srivastava. Pradeep 한국생물공학회 Biotechnology and bioprocess engineering 6 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2009, Vol.14 No.2 207-212 (6 pages)
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Enhanced Production of Phytoestrogenic Isoflavones from Hairy Root Cultures of Psoralea corylifolia L. Using Elicitation and Precursor Feeding
Shinde. Amit N., Malpathak. Nutan, Fulzele. Devanand P. 한국생물공학회 Biotechnology and bioprocess engineering 7 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2009, Vol.14 No.3 288-294 (7 pages)
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Improvement of hEGF Production with Enhanced Cell Division Ability Using Dissolved Oxygen Responses to Pulse Addition of Tryptone
Zheng. Zhi-Yong, Yao. Shan-Jing, Zhan. Xiaobei, Lin. Chi Chung 한국생물공학회 Biotechnology and bioprocess engineering 8 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2009, Vol.14 No.1 52-59 (8 pages)
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Enhanced Cutinase Production of Thermobifida Jusca by a Two-stage Batch and Fed-batch Cultivation Strategy
He. Gangqiang, Huo. Guanghua, Liu. Liming, Zhu. Yang, Du. Guocheng, Chen. Jian 한국생물공학회 Biotechnology and bioprocess engineering 6 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2009, Vol.14 No.1 46-51 (6 pages)
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Simple Fed-batch Cultivation Strategy for the Enhanced Production of a Single-sugar Glucuronic Acid-based Oligosaccharides by a Cellulose-producing Gluconacetobacter hansenii Strain
Khan. Taous, Khan. Salman, Park. Joong-Kon 한국생물공학회 Biotechnology and bioprocess engineering 8 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2008, Vol.13 No.2 240-247 (8 pages)
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Application of Sodium Propionate to the Suspension Culture of Chinese Hamster Ovary Cells for Enhanced Production of Follicle-Stimulating Hormone
Yoon. Sung-Kwan, Ahn. Yong-Ho 한국생물공학회 Biotechnology and bioprocess engineering 5 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2007, Vol.12 No.5 497-501 (5 pages)
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Enhanced Clavulanic Acid Production in Streptomyces clavuligerus NRRL3585 by Overexpression of Regulatory Genes
Hung. Trinh Viet, Ishida. Kenji, Parajuli. Niranjan, Liou. Kwang-Kyoung, Lee. Hei-Chan, Sohng. Jae-Kyung 한국생물공학회 Biotechnology and bioprocess engineering 5 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2006, Vol.11 No.2 116-120 (5 pages)
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Characterization and Enhanced Production of Enterocin HJ35 by Enterococcus faecium HJ35 Isolated from Human Skin
Yoon. Yoh Chang, Park. Hye Jung, Lee. Na-Kyoung, Paik. Hyun-Dong 한국생물공학회 Biotechnology and bioprocess engineering 8 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2005, Vol.10 No.4 296-303 (8 pages)
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Enhanced Production of Succinic Acid by Metabolically Engineered Escherichia coli with Amplified Activities of Malic Enzyme and Fumarase
Hong. Soon-Ho, Lee. Sang-Yup 한국생물공학회 Biotechnology and bioprocess engineering 4 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2004, Vol.9 No.4 252-255 (4 pages)
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Enhanced Production of Cellobiase by a Marine Bacterium, Cellulophaga lytica LBH-14, in Pilot-Scaled Bioreactor Using Rice Bran
고와, 김형우, 이잔홍, 이진우, Cao. Wa, Kim. Hung-Woo, Li. Jianhong, Lee. Jin-Woo 한국생명과학회 생명과학회지 12 Pages
한국생명과학회 생명과학회지 2013, Vol.23 No.4 542-553 (12 pages)
본 연구의 목적은 통계학적 방법을 사용하여 해양미생물 Cellulophaga lytica LBH-14가 생산하는 cellobiase의 생산조건을 확립하는 것이었다. 이 균주의 생육에 최적인 미강, ammonium chloride 및 배지의 초기 pH는 100.0 g/l, 5.00 g/l 및 7.0이었으나, 이 균주가 생산하는 cellobiase의 생산에 최적인 조건은 각각 91.1 g/l, 9.02 g/l 및 6.6이었다. 이 균주의 생육에 최적인 $K_2HPO_4$, NaCl, $MgSO_4{cdot}7H_2O$ 및 $(NH_4)_2SO_4$ 등과 같은 배지의 염농도는 각각 6.25, 0.62, 0.28 및 0.73 g/l이었으나, cellobiase 생산에... -
Enhanced Production of Carboxymethylcellulase by a Newly Isolated Marine Microorganism Bacillus atrophaeus LBH-18 Using Rice Bran, a Byproduct from the Rice Processing Industry
김이준, 고와, 이유정, 이상운, 정정한, 이진우, Kim. Yi-Joon, Cao. Wa, Lee. Yu-Jeong, Lee. Sang-Un, Jeong. Jeong-Han, Lee. Jin-Woo 한국생명과학회 생명과학회지 12 Pages
한국생명과학회 생명과학회지 2012, Vol.22 No.10 1295-1306 (12 pages)
Carboxymethylcellulase를 생산하는 미생물을 해수에서 분리하여 16S rDNA의 염기서열을 분석하고 계통 발생학 방법으로 비교한 결과, Bacillus atrophaeus로 확인되었다. 이 해양 미생물을 B. atrophaeus LBH-18로 명명하였으며 response surface method (RSM)를 사용하여 carboxymethylcellulase의 생산 조건을 최적화하였다. 이 균주의 생육에 최적인 미강, 펩톤 및 배지의 초기 pH는 68.1 g/l, 9.1 g/l 및 7.0이었으나, carboxymethylcellulase의 생산에 최적인 조건은 각각 55.2 g/l, 6.6 g/l 및 7.1이었다. 이 균주의 생육과... -
Enhanced Production of Gellan by Sphingomonas paucibilis NK-2000 with Shifts in Agitation Speed and Aeration Rate after Glucose Feeding into the Medium
이남규, 서형필, 조영배, 손창우, 고와, 이진우, Lee. Nam-Kyu, Seo. Hyung-Phil, Cho. Young-Bai, Son. Chang-Woo, Gao. Wa, Lee. Jin-Woo 한국생명과학회 생명과학회지 8 Pages
한국생명과학회 생명과학회지 2010, Vol.20 No.6 811-818 (8 pages)
Sphingomnas paucibilis NK2000 균주를 사용한 젤란의 최적 교반속도 및 통기량은 각각 400 rpm 및 1.0 vvm이었다. 이 균주를 사용하여 젤란의 생산성을 향상시키기 위한 포도당의 최적 첨가시기는 배양을 시작한 36시간이었다. 젤란의 생산성을 향상시키기 위한 5가지 방법, 1) 포도당을 첨가하지 않는 방법, 2) 배양 36시간 후에 포도당을 첨가하지만 교반속도 및 통기량을 변화시키지 않는 방법, 3) 배양 36 시간 후에 포도당을 첨가하고 교반속도를 400 rpm에서 600 rpm으로 변화시키는 방법, 4) 배양 36 시간 후에 포도당을 첨가하고... -
Enhanced Production of Astaxanthin by Metabolic Engineered Isoprenoid Pathway in Escherichia coli
이재형, 서용배, 김영태, Lee. Jae-Hyung, Seo. Yong-Bae, Kim. Young-Tae 한국생명과학회 생명과학회지 7 Pages
한국생명과학회 생명과학회지 2008, Vol.18 No.12 1764-1770 (7 pages)
이 연구의 목적은 생물공학적으로 이소프레노이드 생합성 유전자를 클로닝하여 이들을 형질전환시킨 대장균을 제조하여 이들을 숙주로 사용하여 아스타잔틴의 생산을 증가시키는 것이다. 본 연구진은 선행연구에서 Paracoccus haeundaensis로부터 아스타잔틴 생산에 관여하는 6개의 아스타잔틴 생합성 유전자군을 보고하였고, 이들 유전자들을 발현 벡타(pCR-XL-TOPO-Crt)에 재조합한 후 이 벡터를 대장균에 형질 전환시켜서 건조중량으로 400 ${mu}g$/g의 아스타잔틴을 생산하였다. 아스타잔틴의 생산성을 증가시키기 위해서... -
Enhanced Production of Exopolysaccharides by Fed-batch Culture of Ganoderma resinaceum DG-6556
Kim. Hyun-Mi, Paik. Soon-Young, Ra. Kyung-Soo, Koo. Kwang-Bon, Yun. Jong-Won, Choi. Jang-Won 한국미생물학회 The journal of microbiology 10 Pages
한국미생물학회 The journal of microbiology 2006, Vol.44 No.2 233-242 (10 pages)
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Enhanced Production of ${varepsilon}$-Caprolactone by Coexpression of Bacterial Hemoglobin Gene in Recombinant Escherichia coli Expressing Cyclohexanone Monooxygenase Gene
Lee. Won-Heong, Park. Eun-Hee, Kim. Myoung-Dong 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2014, Vol.24 No.12 1685-1689 (5 pages)
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Enhanced Biofuel Production from High-Concentration Bioethanol Wastewater by a Newly Isolated Heterotrophic Microalga, Chlorella vulgaris LAM-Q
Xie. Tonghui, Liu. Jing, Du. Kaifeng, Liang. Bin, Zhang. Yongkui 한국미생물생명공학회 Journal of microbiology and biotechnology 12 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2013, Vol.23 No.10 1460-1471 (12 pages)
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Significantly Enhanced Production of Acarbose in Fed-Batch Fermentation with the Addition of S-Adenosylmethionine
Sun. Li-Hui, Li. Ming-Gang, Wang. Yuan-Shan, Zheng. Yu-Guo 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2012, Vol.22 No.6 826-831 (6 pages)
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Enhanced Carboxymethylcellulase Production by a Newly Isolated Marine Bacterium, Cellulophaga lytica LBH-14, Using Rice Bran
Gao. Wa, Lee. Eun-Jung, Lee. Sang-Un, Li. Jianhong, Chung. Chung-Han, Lee. Jin-Woo 한국미생물생명공학회 Journal of microbiology and biotechnology 11 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2012, Vol.22 No.10 1412-1422 (11 pages)
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Enhanced 2,3-Butanediol Production in Recombinant Klebsiella pneumoniae via Overexpression of Synthesis-Related Genes
Kim. Borim, Lee. Soojin, Park. Joohong, Lu. Mingshou, Oh. Minkyu, Kim. Youngrok, Lee. Jinwon 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2012, Vol.22 No.9 1258-1263 (6 pages)
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Enhanced ${varepsilon}$-Poly-$_L$-lysine Production from Streptomyces ahygroscopicus by a Combination of Cell Immobilization and In Situ Adsorption
Liu. Shengrong, Wu. Qingping, Zhang. Jumei, Mo. Shuping, Yang. Xiaojuan, Xiao. Chun 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2012, Vol.22 No.9 1218-1223 (6 pages)
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Enhanced Antibiotic Production by Streptomyces sindenensis Using Artificial Neural Networks Coupled with Genetic Algorithm and Nelder-Mead Downhill Simplex
Tripathi. C.K.M., Khan. Mahvish, Praveen. Vandana, Khan. Saif, Srivastava. Akanksha 한국미생물생명공학회 Journal of microbiology and biotechnology 8 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2012, Vol.22 No.7 939-946 (8 pages)
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Enhanced Flavonoid Production in Streptomyces venezuelae via Metabolic Engineering
Park. Sung-Ryeol, Ahn. Mi-Sun, Han. Ah-Reum, Park. Je-Won, Yoon. Yeo-Joon 한국미생물생명공학회 Journal of microbiology and biotechnology 4 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2011, Vol.21 No.11 1143-1146 (4 pages)
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Optimization of Culture Media for Enhanced Chitinase Production from a Novel Strain of Stenotrophomonas maltophilia Using Response Surface Methodology
Khan. Minhaj Ahmad, Hamid. Rifat, Ahmad. Mahboob, Abdin. M.Z., Javed. Saleem 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2010, Vol.20 No.11 1597-1602 (6 pages)
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Enhanced Production of Human Serum Albumin by Fed-Batch Culture of Hansenula polymorpha with High-Purity Oxygen
Youn. Jong-Kyu, Shang. Longan, Kim. Moon-Il, Jeong. Chang-Moon, Chang. Ho-Nam, Hahm. Moon-Sun, Rhee. Sang-Ki, Kang. Hyun-Ah 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2010, Vol.20 No.11 1534-1538 (5 pages)
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Enhanced Production of ${gamma}$-Aminobutyric Acid Using Rice Bran Extracts by Lactobacillus sakei B2-16
Kook. Moo-Chang, Seo. Myung-Ji, Cheigh. Chan-Ick, Pyun. Yu-Ryang, Cho. Seok-Cheol, Park. Hoon 한국미생물생명공학회 Journal of microbiology and biotechnology 4 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2010, Vol.20 No.4 763-766 (4 pages)
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Use of FT-IR to Identify Enhanced Biomass Production and Biochemical Pool Shifts in the Marine Microalgae, Chlorella ovalis, Cultured in Media Composed of Different Ratios of Deep Seawater and Fermented Animal Wastewater
Kim. Mi-Kyung, Jeune. Kyung-Hee 한국미생물생명공학회 Journal of microbiology and biotechnology 7 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2009, Vol.19 No.10 1206-1212 (7 pages)


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