사람 혈청 속에 있는 L-글루탐산-데히드로게나아제 (GlDH) 및 순수한 GlDH (Sigma사 제품)의 활성은 인삼의 에탄올 추출물(WGpet-alc)에 의해 다같이 증가되었지만, 인삼의 석유에테르 추출물(WGpet)에 의해서는 작은 농도에서도 감소되었다. 이러한 효소활성 증가효과 또는 감소효과는 흰쥐의 간 GlDH에 대한 실험결과와도 여러 점에서 공동된 양상을 나타낸다는 것이 확인되었다.
On the basis of our previous report on the biochemical studies of Ginseng substances, it was attempted to observe the effect of ethanol extract (WGpet-alc) and petroleum ether extract (WGpet) of White Ginseng on the activity of human serum GlDH and pure GlDH in vitro. The activity of human serum GlDH and pure GlDH was significantly increased in the presence of WGpet-alc. On the other hand, an inhibitory effect of WGpet on GlDH was observed even at low concentration. It was also confirmed that these activating and inhibitory effects have the same pattern as the effects on albino rat hepatic GlDH.
