Percutaneous needle aspiration biopsy (PNAB) of suspected pulmonary malignancy is a simple, safe and practical method, so should be used earlier and more frequently to shorten the diangostic interval. In Korea Cancer Center Hospital, 64 patients underwent PNAB with a diagnostic yield of 87.5% 7 patients and a pneumothorax and in 3 patients developed transient hemoptysis. OF 58 malignant lung lesion, 56 were diagnosed correctly, with the identifiable specific cell type. Final results of 8 cases of no-malignant cell on PNAB reveal benign lesion of 4 cases, malignancy of 2cases and loss to follow-up of 2 cases, Most of the pulmonary masses were measured 2-44cm (24 cases) or 4-6cm (19 cases) in size, and distributed in upper lobes (36 cases) and peripheral area (45 cases), topographically.