Over a period of recent two years, 100 patients who had localized pulmonary lesions and underwent percutaneous needle aspiration and biopsy, were analized. There were 56 malignancies and 44 benign lesions. The diagnostic accuracy of malignancy including specific cell type and benign disease are 89% and 79% respectively. Differentiation of malignancy vs. benignity was possible in 89% of cases obviating unnecessary exploratory thoracotomy for diagnostic purpose. Five cases were misinterpreted and eight cases were non-diagnostic on cytology Inadequate material was obtained in two cases ; one was due to hardness of the mass, which, later, confirmed as chondrosarcoma, and the other was too small 80.8x1.0cm) to be visble on lateral view. The obtainability of the tissue was 98% 14(14%) patients developed pneumothorax; one of them required treatment and the remainder showed spontaneous resporption. (Trasient neglibigle blood tinged sputum was found in 16 (16%) cases. The method, problems and complications are discussed. Authors recommend the percutaneous needle asporat aspiration and biopsy wa the initial procedure in diagnostic work-up of pulmonary coin lesions, especially when they are smaller, more peripheral and metastatic neoplasm is suspected.