사람 적혈구에서 [$^{14}C$]-alanine, [$^{14}C$]-glucose, [$^{14}C$]-cholesterol 및 [$^{14}C$]-phosphatidylethanolamine의 흡수를 lysolecithin과 saponin 존재하에서 실험하여 본 결과 다음과 같은 결과를 얻었다. 적혈구를 lysolecithin으로 미리 처리시켰을 때, 상기 물질들의 uptake가 alanine의 경우 최고 111%, glucose는 43%, cholesterol은 48%, phosphatidylethanolamine은 17%의 상승율을 보였고, saponin의 처리에 의해서는 각각 408%, 70%, 28% 및 10%의 상승율을 나타냈다. 두 lytic agent에 의한 상승율은 각각의 최적 농도에서 비교해보면 lysolecithin은 saponin 경우보다 막성분인 cholesterol이나 phosphatidylethanolamine의 uptake에 더 영향을 끼쳤고, 한편 saponin은 alanine과 glucose와 같은 polar metabolite의 uptake에 더 영향을 주는 것으로 확인되었다.
The effects of lysolecithin and ginseng saponin on the uptake of [$^{14}C$]-alanine, [$^{14}C$]-glucose, [$^{14}C$]-cholesterol, and [$^{14}C$]-phosphatidylethanolamine to human erythrocytes in the various conditions were as follows. When the human erythrocytes pretreated in the presence of low lytic amount of lysolecithin, the uptake of such polar metabolites and membrane components was enhanced up to [$^{14}C$]-alanine 111%, [$^{14}C$]-glucose 43%, [$^{14}C$]-cholesterol 48%, and [$^{14}C$]-phosphatidylethanolamine 17%, In case of saponin pretreatment, the uptakes of such substances were increased to 408%, 70%, 28%, and 10%, respectively. In comparison with both lytic surfactants under the optimum concentration, lysolecithin was more effective to the uptake of membrane components, cholesterol and phosphatidylethanolamine. On the other hand, saponin was more potent to the polar metabolite uptake into the erythrocytes.
