99mTc-DMSA(dimercaptosuccinic acid) renal uptake rates have provided an index for the cortical functioning mass and also made feasible a quantitative assessment of differential renal function by setting up a regression equation such as y=0.841x-4.5746(y: quantitative renal uptake rate, x: simple renal uptake rate). The author have investigated 99mTc-DMSA renal uptake rates in order to evaluate the renal function according to 1 group with normal kidney and 5 groups with renal diseases and to compare with serum BUN and creatinine in 335 cases which underwent 99mTc-DMSA renal scintigram during the last 3 years at Pusan National University Hospital. The quantitative renal uptake rates of 99mTc-DMSA at 3 hours after intravenous injection were 50.1$pm$1.5% in the normal kidndys group, 49.2$pm$3.4% in the healthy solitary kidney group, 28.3$pm$3.9% in the pathologic solitary kidneys group, 45.9$pm$1.3% in the unilateral nephropathy group, 26.0$pm$3.2% in the bilateral symmetric nephropathy group, and 32.3$pm$3.9% in the bilateral dissymmetric nephropathy group. When the diagnostic sensitivity of 99mTc-DMSA renal uptake rates was compared with those of serum BUN and creatinine, the 99mTc-DMSA renal uptake rates were more sinsitive than the latter in the true positive ratio. The 99mTc-DMSA renal scintigram provides good renal image qualiaty concomitantly. So 99mTc-DMSA renal scintigram could provide important clues in determinig the diagnosis, therapeutic effectiveness, and prognosis of renal diseases.