The tobbaco cut worm, Spodoptera litura, like some other insects, has unique wound- healing processes against injury at a cuticle and its associated epidermis. Actually this insect proceeds healing processes at an injured point by cellular immune reaction. However, these wound healing processes appeared to be more complicate responses than usual cellular immune responses in which most insects Occured. The present investigation, which was using light microscope and electron microscope, was performed to clarify described early wound-healing processes against the injury made by artificial puncture at a point of cuticle and its associated epidermis in dorsal part of the fourth segment of tabboco cut worm. Within 2 minutes the punctured injury as clogged by haemolymph proteins. Following 30 minutes of the puncture, a few cluster of haemocytes gathered around injured part. And 60 minutes later, many granulocytes converged near the basement membrane of the epidermis beneath injured cuticles, and secreted their granules to basement membrane. On the suburbs of granulocytes, then plasmatocytes are elongated and flattened to contact with each other. The granulocytes maintained to contain less granules 90 minutes later, and also appeared to rearrange into the monolayer at disrupting region of epidermal layer. Plasmatocytes adhered completely to each other to form clot for serving a mechanical barrier. In summary, almost all haemocytes including especially granulocytes and plasmatocytes, should involved this wound-healing processes actively. So, this investigation emphasis that haemocytes play more important role in the early wound-healing processes than haemolymph proteins.