Immdeiate hypersensitivity reactions to natural rubber and latex products pose a significant threat to patients, healthcare workers, and the general population. The purpose of this study is to summarize the clinical syomptoms of latex rubber allergy and provide guidelines for the management of latex allergy. Contact dermatitis from the nearly constant use of latex gloves during the workday has become a real problem for many health care professionals. Moreover, the patient who come in contact with these gloves or with other latex-containing equipment may show reactons. Far worse than skin problems is life-threatening anaphyaxis, which can be the first indication that a person has latex sensitivity. In conclusion, nurses shold know the latex precautions such as risk factors, adverse reactons to latex, emergent treatment and so on.