We propose the various Telemedicine applications using collaborative PACS environment. Traditionally, almost all medical images have been printed on radiological films. These films are expensive to produce and easy to misplace and usually only one copy exists, thus limiting the number of persons who have simultaneous access to the images. But the merit of this system including PACS(Picture Archiving and Communications System ) is very many which are small depository, low maintenance expense, good efficience(storage, speed) and good flexibility but the development costs is higher. This research has been done creating multimedia-based Telemedicine system for home PCs in network environment. Most of Telemedicine used hardware and exclusive line of high cost as CATV broadcasting technique. But this system will contribute to change the Home-PC for better use of collaborations among doctor and patients through various modes of interactions in cyberspace.