Logistics systems can be evaluated by how productively distribution center operates, how promptly transportation vehicle dispatches, how efficiently facility layout is, and so on. In this paper, a practical vehicle routing scheme with fixed delivery time and fixed vehicle routes is introduced. The method helps the distribution center reduce logistics cost with respect to dispatching vehicles, and satisfy the customer with pre-determined delivery time window constraints. A case study has shown that the proposed scheme not only generates a feasible schedule with time windows, but also balances material flow in warehouse.