Purpose: To evaluate the efficacy of erythromycin(EM) , known to accelerate gastric emptying, in modified small -bowel follow-through (SBFT). Materials and Methods: We evaluated 32 normal patients who underwent modified SBFT by oral administration of methylcellulose. In the EM injection group (n = 20),500 mg EM (3 mg/kg in pediatric patients) in 100 ml saline was infused intravenously over a 15-minute period prior to the administration of a barium meal, whilein the control group (n= 12), EM was not infused. Gastric empaling time(GET), small-bowel transit time(SBTT) for barium and methylcellulose, small-bowel transit(SBT) during the first 15 minutes, luminal diameter and quality of image were compared between the two groups. SBT was assigned 1,2,3, or 4 points, depending on the extent to which the barium head reached the proximal or distal jejunum, and the proximal or distal ileum during the initial 15-minute. Three radiologists reached a consensus as to image quality. Resu1ts: Mean GET was significantly faster in the EM injection group fl8.5 mins for 150 ml bariLlm suspension and 25.8 mins for 600 ml methylcellulosel . The SBT score during the initial 15 minutes was significantly higher in the EM i7ection group 13.3 pointsl than in the control group 12.4 points>, but mean SBTT was not significantly different between the two groups. Luminal diameter and image quality were also higher in the EM injection group. Conclusion: EM does not decrease SBTT but is highly effective for shortening gastric emptying time, helping to increase the range of fluoroscopic examination and improve image quality in modified small-bowel followthrough, especially in patients with delayed gastric empaling.