In the maintenance and retrofit planning of a bridge system, the optimal strategy for inspection and repair are suggested by minimizing the expected total life-cycle cost, which includes the initial cost, the costs of inspection, repair, and failure. Degradation of seismic performance is modeled by using a damage function. And failure probability is computed according to the degree of damage detection by random vibration theory and the event tree analysis. As an example to illustrate the proposed approach, a 10-span continuous bridge structure is used. The numerical results show that the optimum number of the inspection and the repair are increased, as the seismic intensity is increased and the soil condition of a site becomes more flexible.