In Korea, air source heat pump system is less efficient than conventional heat source facilities, because the air temperature in winter season is so low that COP of air source heat pump system drops below 3.0. Therefore, the study on the application of heat pump heating and cooling systems is crucial for the efficient popularization of heat pump. In this work, we present the dynamic analysis of energy consumption for the large hospital building by heat resistance-capacitance method. The system simulation of water storage air source heat pump is additionally performed by changing sizes and locations of the hospital building. The computed results show that energy cost of water storage air source heat pump is low, so it is more economical than absorption chiller & heater.