Feasibilities of the application of a micro gas turbine cogeneration system to a large size hospital building are studied by estimating energy demands and supplies. The energy demand for electricity is estimated by surveying and sorting the consumption records for various equipment and devices. The cooling heating, and hot water demands are further refined with TRNSYS and ESP-r to generate load profiles for the subsequent operation simulations. The operation of the suggested cogeneration system in conjunction with the load data is simulated for a time span of a year to predict energy consumption and gain profile. The simulation revealed that the thermal efficiency of the gas turbine is about 30% and it supplies 60% of the electricity required by the building. The recovered heat can meet 56% of total heating load and 67% of cooling, and the combined efficiency reaches up to 70%.