Recently, the aim of cold storage warehouse is not only to provide preservation of the quality of perishable foods but also to use state-of-the-art information systems to rapidly move products across the cold chain. An RFID (Radio Frequency Identification) is an automatic identification method that detects signals from mobile objects, and tracks and traces movement of the objects. RFID can be used to turn a cold storage warehouses into a real-time system. In this paper, we develop an cold storage management system to support the optimized business processes with RFID system. First of all, business processes in the cold storage warehouse are analyzed. Then design factors which should be considered for incorporating RFID are defined. Design values which set to the design factors can be extracted from using RFID deployment simulator. as a result, the design values make RFID to be efficiently integrated to existing business processes.