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Comparison of mild ovarian stimulation with conventional ovarian stimulation in poor responders
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  • Comparison of mild ovarian stimulation with conventional ovarian stimulation in poor responders
  • Comparison of mild ovarian stimulation with conventional ovarian stimulation in poor responders
저자명
Yoo. Ji-Hee,Cha. Sun-Hwa,Park. Chan-Woo,Kim. Jin-Young,Yang. Kwang-Moon,Song. In-Ok,Koong. Mi-Kyoung,Kang. Inn-Soo,Kim. Hye-Ok
간행물명
Clinical and experimental reproductive medicine
권/호정보
2011년|38권 3호|pp.159-163 (5 pages)
발행정보
대한생식의학회
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정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Objective: To compare the IVF outcomes of mild ovarian stimulation with conventional ovarian stimulation in poor responders. Methods: From 2004 to 2009, 389 IVF cycles in 285 women showed poor responses (defined as either a basal FSH level ${geq}$12 mIU/mL, or the number of retrieved oocytes ${leq}$3, or serum $E_2$ level on hCG day <500 pg/mL) were analyzed, retrospectively. In total, 119 cycles with mild ovarian stimulation (m-IVF) and 270 cycles with conventional ovarian stimulation (c-IVF) were included. Both groups were divided based on their age, into groups over and under 37 years old. Results: The m-IVF group was lower than the c-IVF group in the duration of stimulation, total doses of gonadotropins used, serum $E_2$ level on hCG day, the number of retrieved oocytes, and the number of mature oocytes. However, there was no significant difference in the number of good embryos, the number of transferred embryos, the cancellation rate, or the clinical pregnancy rate. In the m-IVF group over 37 years old, the clinical pregnancy rate and live birth rate were higher when compared with the c-IVF group, but this result was not statistically significant. Conclusion: In poor responder groups, mild ovarian stimulation is more cost effective and patient friendly than conventional IVF. Therefore, we suggest that mild ovarian stimulation could be considered for poor responders over 37 years old.