Purpose: The purpose of this research was to determine the effects of hospice and palliative care education on knowledge of hospice and palliative care and attitude toward death in nursing students. Method: Subjects of this study included 49 nursing students. Using a one-group pretest-posttest quasi-experimental research design, we conducted experiments to determine the effects of a hospice and palliative care education during a period of seven weeks from August through November 2009. The program was composed of seven sessions (total: 28hrs). The SPSS/Win 18.0 program was used for analysis of collected data. Results: A significant change in knowledge of hospice and palliative care and attitude toward death was observed after the intervention. Conclusion: The hospice and palliative care education was effective for nursing students in improving their attitude toward death and in increasing knowledge of hospice and palliative care. Therefore, I recommend generous application of this program to nursing students in order to improve knowledge of hospice and palliative care and attitude toward death.