The purpose of this study was compared the spray, combustion and emissions (NOx, CO, HC, smoke) characteristics of a typical fuel (100% Diesel, DME) and Diesel-DME blended fuel in a Constant Volume Chamber (CVC) and a single-cylinder DI diesel engine. Spray characteristics were investigated under various ambient and fuel injection pressures when the Diesel-DME blended ratio is varied. The parameters of spray sturdy were spray shape, penetration length, and spray angle. Common types of injectors having seven holes and made by Bosch were used. As of use, the typical fuel (100% Diesel, DME) and the blended fuel by mixture ratio 95:5, 90:10 (Diesel:DME) were used. The Injection pressure was fixed by 70.1MPa, when the ambient Pressure was varied 0.1, 2.6 and 5.1 MPa. The combustion experiments was conducted with single cylinder engine equipped with common rail injection system. injection pressure is 70 MPa. The amount of injected fuels is adjusted to obtain the fixed input calorie value as 972.2 J/cycle in order to compare with the fuel conditions.