Parkinson’s Disease identified as a neuro-degenerative disease that the dopamine neurons in the subtantia nigra is progressively destroyed. Tremor at rest, bradykinesia, muscle stiffness and postural reflex impairment are the most common symptoms of Parkinson’s disease. Also the slow progression of disease is common in Parkinson’s disease. Causes of the disease have been discovered by researchers but the cure of the disease, regenerating or generate the dopamine neurons, are still unclear. Recent studies report the exercise can help the regenerate or generate the dopamine neurons of animal models of PD. Also the physical exercise may assuage the symptoms of parkinson’s disease and depression is reported by several clinical researches. In the present study, we used the model of drosophila PD and compare the effects of 3day exercise per week group and 7day exercise per week group. The results of 6week aerobic exercise on the LRRK2 PD model say the 3day exercise group has more dopamine neurons and better locomotor ability than the 7day exercise group. This result follows previous studies that are report low intensity exercise could gain more benefits than high intensity exercise. We could presume that the result of this came from lower recovery ability of PD models. So, we suggest that the PD patients could gain more benefits by doing exercise every other day.