치과에서 임플란트를 이용한 보철치료가 보급됨에 따라 임플란트 주위 질환의 발생 빈도가 높아지게 되어1), 이에 대한 적절하고 효과 적인 치료 방법이 계속적으로 연구되고 있다. 현재의 치료 방법으로 는 비외과적 치료방법6)과 외과적 치료방법7)으로 구분되며, 비외과적 치료법으로 항생제, 소파술(curettage), 초음파 세정술(ultrasonic scaling), 레이저(laser) 등이 이용되고 있다2,8). 그러나 비외과적인 다양한 치료법의 다양한 시도에도 불구하고 임플란트주위염에 대해 적용이 편리하고 명확한 결과를 보이는 치료법은 아직 없는 실정이 다3). Diode Laser 치료 방법은 치주염 치료에서 많이 이용되었으 며, 임상적 데이터와 치료결과에 긍정적 영향을 가지고 있다9). 그러 나 Diode laser를 임플란트주위염에 적용하여 치료효과를 살펴본 실험데이터는 미미한 상태이며, titanium 금속에 Diode laser를 조사하였을 때 열 발생이나 표면 변화 그리고 세균 조절의 정도 등에 대한 연구는 미흡하다. 본 연구는 in vitro, in vivo 연구를 통하여 임플란트주위염에 새 로 개발된 Diode laser (808 nm)를 이용하여 치료가 얼마만큼 효 과적이고 안전한지를 평가하고자 하였으며, 기존 출시된 Picasso Diode laser (810 nm)와 같이 비교 효능 조사를 시행하였다.
Purpose: Peri-implantitis is defined by an inflammation that occurs at the soft tissue and the alveolar bone around the site of an implant. The failure of implant placement or the loss of the supporting bone may occur due to peri-implantitis. From a pathological perspective, A. actinomycetemcomitans, Capnocytophaga sp., F. nucleatum, or other infectious agent is seen as the cause of the peri-implantitis. To remove the cause of the disease, many non-invasive methods are being studied. In this study, we demonstrated decontamination of the implant surface and its surroundings through experiments using diode laser products in existing products and diode laser experiments that studied the effect on the decreasing peri-implants. Materials and Methods: 12-week-old male Sprague-Dawley rats weighing 300 g were purchased. The size of 1.2 * 4 mm hole was drilled into the hard plate of the maxillary bone to insert titanium screw implant. Test groups were divided into control, titanium screw implant group, peri-implantitis group, and laser-treated peri-implantitis group. Infection levels around the site of implants were checked with SEM. The degree of microbial reproduction was checked through real-time PCR (qPCR) for each group. Results: The use of 808 nm Diode laser (0.5 w, 15 seconds in continuous mode) to treat the inflammation caused by peri-implantitis in the soft tissue and the alveolar bone resulted in an effective reduction in the number of bacteria without the surface denaturation of the implant due to the laser. In comparison to the existing products, such as Picaso Diode laser (810 nm) and Bison Diode laser (808 nm), both products have shown effectiveness in eliminating bacteria. In particular, 808 nm Diode laser showed equal effectiveness to the 810 nm Diode laser at a lower temperature. Conclusion: Peri-implantitis was treated in the inflammation region of soft tissue and alveolar bone using the 808 nm and 810 nm Diode laser in continuous mode at 0.5 w for 15 seconds. As a result, laser-induced excessive heat generation or denaturation on the implant surfaces did not occur and the number of bacteriadecreased. (JOURNAL OF DENTAL IMPLANT RESEARCH 2016;35(1):1-8)
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