The purpose of this paper is the development of Problem Based Learning Module for Nursing Clinical Practice. Specific research tasks are as follows; 1. Design the draft of Problem Based Learning Module by inquiring the references 2. Do the formative test for the draft Problem Based Learning Module 3. Suppose the development of Problem Based Learning Module for Nursing Clinical Practice The formative test was done for evaluating the validity of the draft. The subjects of this test were 25 nursing students who were 3th grade in the department of Nursing, P University. The application period was four months. The method for the formative test was pursued by various angles. In this paper, the strategies of the design for Problem Based Learning Module for Nursing Clinical Practice is as follows; first, consider nursing practice environment such as hospital environment, nurses and patients. Second, follow the characteristics of Problem Based Learning such as self-directed, problem solving, team learning, special knowledge acquisition, facilitator, blended learning. Third, make the structural frame in order to apply to nursing clinical practice universally. The core learning process of this paper contains five steps such as authentic problems, nursing needs, learning tasks, solution finding & verification, and reflection. The blue print of this paper contains entire agenda and learning module. The entire process map of this paper schematizes the whole learning processes. This map consists of pre_session, learning module I, II, III, and post_session.