Objective: This study was performed to measure the level of stress of cerebral palsy workers, and to investigate the relationship between the stress dimensions and stress inducing factors of cerebral palsy workers in Korean manufacturing industry. Method: The sample used in this study consists of 66 employees with cerebral palsy wokers. They are employees of the protective employment companies located in Seoul, Inchon, and Gyung-gi province. The Psycho-Social Well-being Index (PWI), which was designed through modification of Goldberg’s 60-items of General Health Questionnaire (GHQ), was used to measure the stress level. The following variables, independent and moderate variables, are designed for the same purpose. The independent variables are general and disability characteristics, workplace-related characteristics of the respondents. The moderate variables include social support, type A behavior pattern, self-esteem and coping strategy. The collected data were analyzed using SAS version 6.12 program. Results: The results of this study were summarized as follows; 1.　For the moderate variables, the low self esteem, and A type behavior were more significant to measure the stress level. 2.　The multiple regression analysis showed that the significant variables on the level of stress of cerebral palsy workers were low self-esteem and A type behavior pattern. Conclusion: The results of this study suggest that appropriate health promotion programs, should be established and provided for reducing the stress of cerebral palsy workers in manufacturing industry.