The purpose of this study was to examine the effects of group cognitive behavioral art therapy on the social anxiety and self-esteem of female undergraduates with social anxiety tendency. Several female students with difficulties in interpersonal relationships or speech were recruited from a university. Then, group cognitive behavioral art therapy with 10 sessions were conducted, and pre-post test scores were compared to investigate the differences between participants’ social anxiety and self-esteem at both time points. The following quantitative measures were used: Social Avoidance and Distress Scale (SADS) and Speech Anxiety Scale (SAS) for the social anxiety variable, and Self-Esteem Scale (SES) for the self-esteem variable. The results revealed that, after the program, participants experienced (a) reduced social avoidance and distress, (b) decreased speech anxiety, and (c) increased self-esteem significantly. In sum, group cognitive behavioral art therapy in this study reduced the female undergraduate students social anxiety and enhanced their self-esteem. Lastly, the limitations of this study and possible future studies were discussed.