This study is to explore how the internalized shame and perfectionism acts as an influencing factor in Christian university students who have a high tendency of interpersonal problem. 485 Christian university students were surveyed, and were classified into groups having a high and low tendency of interpersonal problem. t–test, correlation analysis and multiple regression analysis were conducted. The results are as follows. First, there was a significant difference between high and low interpersonal problem tendency groups. Second, in case of a low interpersonal problem tendency group, ‘anxiety of making a mistake’ in internalized shame had a significant effect on interpersonal problem, and in case of a high interpersonal problem tendency group, ‘socially imposed perfectionism’ in perfectionism do. Third, in the results of analyzing an effect of internalized shame and perfectionism to interpersonal problem tendency, only high interpersonal problem tendency group was affected by both internalized shame and perfectionism. It is expected that the results of this study will be helpful to set an education and counseling strategy for Christian university students’ interpersonal problem solving.