The purpose of this study was to investigate the effectiveness of Neuro-Linguistic Programming (NLP) as an intervention model for resolving family conflicts. The study was based on the idea that trauma experienced by a client in childhood with his or her family of origin exerts a negative influence on the client’s current family relations. The researchers of this study have attempted to promote the application of NLP to the domestic family therapy field. Methods: This study was a case study with seven families who have suffered from childhood traumas in their family of origin. Results: After a rapport was established, NLP techniques were applied in the early stages of the family therapy processes, across an average of 2-3 sessions, and the standard family therapy procedures were conducted for the rest of the sessions. The therapeutic effectiveness of NLP was confirmed in all cases. In particular, the re-experiencing of painful feelings, which is the main traumatic symptom, was substantially reduced. Empathetic understandings from the clients' spouses or family members increased when they were allowed to watch the NLP intervention process, which resulted in enhancing their relationships. Also, through sensory awareness training helped them to improve mutual understandings. Conclusions: As a result, communication and other relational coping skills were significantly improved, accelerating changes in family relations. The conceptual bases of this study were the synesthetic characteristics of trauma, neuroplasticity, and the concept of positive psychology. In addition, the theoretical basis and techniques of multigenerational, experiential, narrative, and solution-focused family therapy models were integratively applied.