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Constituents of the Stems of Rumex japonicus with Advanced Glycation End Products (AGEs) and Rat Lens Aldose Reductase (RLAR) Inhibitory Activity
Kim. Jong-Min, Lee. Yun-Mi, Jang. Dae-Sik, Kim. Jin-Sook 한국응용생명화학회 Agricultural chemistry & biotechnology 4 Pages
한국응용생명화학회 Agricultural chemistry & biotechnology 2006, Vol.49 No.1 24-27 (4 pages)
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Constituents of the Flowers of Erigeron annuus with Inhibitory activity on the Formation of Advanced Glycation End Products (AGEs) and Aldose Reductase
Jang. Dae-Sik, Yoo. Nam-Hee, Lee. Yun-Mi, Yoo. Jeong-Lim, Kim. Young-Sook, Kim. Jin-Sook 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 5 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2008, Vol.31 No.7 900-904 (5 pages)
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Constituents of the Roots of Pueraria Iobata Inhibit Formation of Advanced Glycation End Products (AGEs)
Kim. Jong-Min, Lee. Yun-Mi, Lee. Ga-Young, Jang. Dae-Sik, Bae. Ki-Hwan, Kim. Jin-Sook 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 5 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2006, Vol.29 No.10 821-825 (5 pages)
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Naphthopyrone Glucosides from the Seeds of Cassia tora with Inhibitory Activity on Advanced Glycation End Products (AGEs) Formation
Lee. Ga-Young, Jang. Dae-Sik, Lee. Yun-Mi, Kim. Jong-Min, Kim. Jin-Sook 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 4 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2006, Vol.29 No.7 587-590 (4 pages)
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Advanced Glycation End Products and Diabetic Complications
VarunParkashSingh, AnjanaBali, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 1 1-14 (14 pages)
known as glycation. Protein glycation and formation of advanced glycation end products (AGEs) play an important role in the pathogenesis of diabetic complications like retinopathy, nephropathy, neuropathy, cardiomyopathy along with some other diseases such as rheumatoid arthritis, osteoporosis and aging. Glycation of proteins interferes with their normal functions by disrupting molecular conformation, altering enzymatic activity, and interfering with receptor functioning. AGEs form intra- and... -
Regulator of Calcineurin 1 Isoform 4 (RCAN1.4) Is Overexpressed in the Glomeruli of Diabetic Mice
ChorongJang, JiHeeLim, CheolWheePark, Young-JinCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.5 8 299-306 (8 pages)
Calcineurin (CaN) is activated in diabetes and plays a role in glomerular hypertrophy and extracellular matrix (ECM) accumulation. Here, kidneys from diabetic model mice were investigated for the expression of the regulator of CaN 1 (RCAN1) isoform 4 (RCAN1.4) which had been shown to be transcriptionally upregulated by CaN activation. We found the increased immunoreactivity for RCAN1 in the glomerular cells of db/db mice and streptozotocin-induced diabetic mice. In concordance, the expression of... -
중국 약용식물의 최종당화산물 생성저해활성 검색 (X)
김영숙, 이윤미, 김주환, 김진숙, Kim. Young Sook, Lee. Yun Mi, Kim. Joo Hwan, Kim. Jin Sook 한국생약학회 생약학회지 7 Pages
한국생약학회 생약학회지 2013, Vol.44 No.3 305-311 (7 pages)
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한국약용식물의 최종당화산물 생성저해활성 검색 (IX)
이윤미, 김영숙, 김주환, 김진숙, Lee. Yun Mi, Kim. Young Sook, Kim. Joo Hwan, Kim. Jin Sook 한국생약학회 생약학회지 7 Pages
한국생약학회 생약학회지 2013, Vol.44 No.3 298-304 (7 pages)
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한국약용식물의 최종당화산물 생성저해활성 검색 (XI)
최소진, 김영숙, 송유진, 김주환, 김진숙, Choi. So Jin, Kim. Young Sook, Song. Yoo Jin, Kim. Joo Hwan, Kim. Jin Sook 한국생약학회 생약학회지 7 Pages
한국생약학회 생약학회지 2013, Vol.44 No.4 372-378 (7 pages)
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중국산 약용식물의 최종당화산물 생성저해활성 검색 (V)
김영숙, 최성훈, 김주환, 김진숙, Kim. Young-Sook, Choi. Sung-Hoon, Kim. Joo-Hwan, Kim. Jin-Sook 한국생약학회 생약학회지 8 Pages
한국생약학회 생약학회지 2011, Vol.42 No.1 46-53 (8 pages)
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중국, 베트남산 약용식물의 최종당화산물 생성저해활성 검색 (IV)
김종민, 김영숙, 김주환, 유정림, 김진숙, Kim. Jong-Min, Kim. Young-Sook, Kim. Joo-Hwan, Yoo. Jeong-Lim, Kim. Jin-Sook 한국생약학회 생약학회지 6 Pages
한국생약학회 생약학회지 2009, Vol.40 No.4 388-393 (6 pages)
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한국약용식물의 최종당화산물 생성저해활성 검색 (II)
이윤미, 김영숙, 김종민, 장대식, 김주환, 유정림, 김진숙, Lee. Yun-Mi, Kim. Young-Sook, Kim. Jong-Min, Jang. Dae-Sik, Kim. Joo-Hwan, Yoo. Jeong-Lim, Kim. Jin-Sook 한국생약학회 생약학회지 5 Pages
한국생약학회 생약학회지 2008, Vol.39 No.3 223-227 (5 pages)
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한국약용식물의 최종당화산물 생성저해활성 검색(VII)
최소진, 김영숙, 송유진, 이윤미, 김주환, 김진숙, Choi. So-Jin, Kim. Young Sook, Song. Yoo Jin, Lee. Yun Mi, Kim. Joo Hwan, Kim. Jin Sook 한국생약학회 생약학회지 7 Pages
한국생약학회 생약학회지 2012, Vol.43 No.4 345-351 (7 pages)
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중국.베트남 약용식물의 최종당화산물 생성저해활성 검색(VIII)
최소진, 송유진, 김영숙, 김주환, 김진숙, Choi. So-Jin, Song. Yoo Jin, Kim. Young Sook, Kim. Joo Hwan, Kim. Jin Sook 한국생약학회 생약학회지 7 Pages
한국생약학회 생약학회지 2012, Vol.43 No.4 338-344 (7 pages)
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Sodium butyrate has context-dependent actions on dipeptidyl peptidase-4 and other metabolic parameters
Eun-SolLee, Dong-SungLee, PrakashRajPeya, Youn-ChulKim, Dae-GilKang, Ho-SubLee, Byung-ChulOh, DaeHoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 7 519-529 (11 pages)
Sodium butyrate (SB) has various metabolic actions. However, its effect on dipeptidyl peptidase 4 (DPP-4) needs to be studied further. We aimed to evaluate the metabolic actions of SB, considering its physiologically relevant concentration. We evaluated the effect of SB on regulation of DPP-4 and its other metabolic actions, both in vitro (HepG2 cells and mouse mesangial cells) and in vivo (high fat diet [HFD]-induced obese mice). Ten-week HFD-induced obese C57BL/6J mice were subjected to SB... -
High Glucose Induces Connective Tissue Growth Factor Expression and Extracellular Matrix Accumulation in Rat Aorta Vascular Smooth Muscle Cells Via Extracellular Signal-Regulated Kinase 1/2
YuMiHa, DongHyupLee, MinaKim, YoungJinKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 8 307-314 (8 pages)
Connective tissue growth factor (CTGF) is a potent pro-fibrotic factor, which is implicated in fibrosis through extracellular matrix (ECM) induction in diabetic cardiovascular complications. It is an important downstream mediator in the fibrotic action of transforming growth factor Ղ (TGFՂ) and is potentially induced by hyperglycemia in human vascular smooth muscle cells (VSMCs). Therefore, the goal of this study is to identify the signaling pathways of CTGF effects on ECM... -
Anti-Apoptotic Effect of Rheum undulatum Water Extract in Pancreatic β-cell Line,
SeoHyunYoon, MeeSookHong, JooHoChung, SungHyunChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 8 51-55 (5 pages)
Sopungsungi-won has been used as a traditional medicine for diabetes and it has been proved to be a potential remedy for type 2 diabetes mellitus. We previously reported that water extract of Sopungsungi-won exhibits anti-diabetic effects both in vivo and in vitro experiments. In the present study, we have chosen to examined anti-apoptotic effect of Rheum undulatum, which is the main component of Sopungsungi-won, on pancreatic β-cells, HIT-T15, against hydrogen peroxide (H2O2). oxidative... -
Effects of Carnosine and Related Compounds on Monosaccharide Autoxidation and H2O2 Formation
BeomJunLee, KyungSunKang, SangYoonNam, JaeHakPark, YongSoonLee, YoungWonYun, MyungHaingCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 3 251-261 (11 pages)
manner in the presence of 10 μM Cu (II). The presence of human serum albumin (HSA) decreased their effect on H2O2 formation. Carnosine and anserine has a biphasic effect on α-ketoaldehyde formation from glucose autoxidation. CRCs inhibited glycation of HSA as determined by hydroxymethyl furfural, lysine residue with free ε-amino group, and fructosamine assay. These results suggest that CRCs may be protective against diabetic complications by reacting with sugars and protecting glycation of...
