In the 88 cases of biliary disease, which was proven in Seoul Red Cross Hospital from Jan. 1980 to Dec. 1981, comparative studies were made with oral and IV cholecystochlangiographic findings and ultrasonographic findings. The results were : 1. In the 18 cases of GB stones, there are 17 cases (94.4%) of positive findings in cholecysto-cholangio-graphy with detection of stone in 7 cases (38.9%), while in sonographic study, 16 cases (88.9%) are shown positive findings with detection of stone in 11 cases (61.1%). 2. In the 17 cases of acalculous cholecystitis, the diagnostic accuarcy is 88.2% in cholecystocholangio-graphy and 64.7% in sonography. 3. In the 7 cases of CBD stones, all cases are shown positive findings in cholecystocholangiography with detection of stone in only one case (14.3%), while 6 cases (85.7%) of positive findings are shown in sonography with detection of stone in all cases. 4. IV. cholangigraphy is more accurate diagnostic procedure rather than oral GB study in the cases of poor or non-functioning GB. 5. Sonography is the choice of plrocedure in the diagnosis of stones, while in the cases of cholecystitis, cholecystocholangiography is more useful diagnostic procedure.