The purpose of this study was to explore the anticipated positive effects of Web-based anchored program on pre-service general education teachers‘ understanding of students with disabilities and instructional adaptations. In particular, currently Korean teacher educators face new challenges; teaching pre-service general education teachers to understand students with disabilities and instructional strategies that are effective in inclusive classroom settings. However, it does not seem to be easy because of two reasons. First, there are not enough teacher educators for this. Second, there is no well-structured curriculum for pre-service general education teachers that is well matched in inclusive classroom settings. Previous studies on Web-based anchored instruction for the pre-service general education teachers indicated that this approach would be effective on pre-service teachers' 1) knowledge transfer, reflective thinking, attitude and motivation, and 2) use of ICT in terms of teaching and learning perspective. In addition, Web-based anchored program seems to be effective on teaching large number of students with small number of teacher educators with well-prepared curriculum, use of multimedia resources, increasing interactions, and individualized learning.