This study explored how the satisfaction with family relationships of middle-aged married people (30-59 years old) changed from 2017 to 2020, taking into account gender differences, gender roles, and depressive factors. Study data extracted from 3,136 men and women aged 30 to 59 in 2017, the reference point in the Korean Welfare Panel data. The extracted data was analyzed through a latent growth model based on a structural equation model and the main research results are as follows. First, there was an increase in family relationship satisfaction among all the subjects of the sample, but looking at the gender difference, the increase in family relationship satisfaction was found to be statistically significant in middle-aged married people. Second, gender roles and depression significantly explained the increase in family relationship satisfaction. Third, in the case of middle-aged married people, gender role and depression in the base year significantly predicted the degree of satisfaction with family relationships in the base year. In the case of middle-aged married people, gender role depression in the base year significantly predicted the degree of change in family relationship satisfaction. Summarizing the above results, it seems that there is a gender difference in the family relationship satisfaction trend, and the influence of gender roles and depression on family relationship satisfaction also appears to have some gender differences.