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전체 선택해제
총 39건 검색
본문검색 결과만 보기
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PubMine: An Ontology-Based Text Mining System for Deducing Relationships among Biological Entities
Kim. Tae-Kyung, Oh. Jeong-Su, Ko. Gun-Hwan, Cho. Wan-Sup, Hou. Bo-Kyeng, Lee. Sang-Hyuk 한국생물정보시스템생물학회 Interdisciplinary Bio Central 2 Pages
한국생물정보시스템생물학회 Interdisciplinary Bio Central 2011, Vol.3 No.2 7-8 (2 pages)
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A Design of K-XMDR Search System Using Topic Maps
Jialei. Zhang, Hwang. Chi-Gon, Jung. Gye-Dong, Choi. Young-Keun 한국정보통신학회 International journal of maritime information and communication sciences 8 Pages
한국정보통신학회 International journal of maritime information and communication sciences 2011, Vol.9 No.3 287-294 (8 pages)
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Charting the proteome of Cryptosporidium parvum sporozoites using sequence similarity-based BLAST searching
A.M.A.M.Z. Siddiki*, Jonathan M. Wastling 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 3호 5 203-210 (8 pages)
is a database search protocol for identifying unknown proteins by sequence similarity to homologous proteins using peptide sequences produced by mass spectrometry. We have used several complementary approaches to explore the global sporozoite proteome of C. parvum with available proteomic tools. To optimize the output of the MS data, a sequence similarity-based MS BLAST strategy was employed for bioinformatic analysis. Most significantly, almost all the constituents of glycolysis and several... -
Mass Spectrometry Based Quantitative Proteomic Profiling of Hepatocellular Carcinoma Cell Line
Suchismita Raha, Ho Jeong Lee, Venu Venkatarame Gowda Saralamma, Silvia Yumnam, Jeong Doo Heo, Sang Joon Lee, Eun Hee Kim, Gon Sup Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 92 134-135 (2 pages)
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A two-component signal transduction system contributes to the virulence of Riemerella anatipestifer
Qing Wang, Mianmian Chen, Wei Zhang 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 12 260-270 (11 pages)
Similar to other studies of bacterial pathogens, current studies of the pathogenesis of Riemerella anatipestifer (RA) are focused mainly on in vitro culture conditions. To elucidate further the pathogenesis of RA in vivo, bacterial RNA was extracted from overnight tryptic soy broth cultures (in vitro) and from the blood of infected ducks (in vivo) for comparative RNA sequencing analysis. In total, 682 upregulated genes were identified in vivo. Among the upregulated genes, a signal transduction... -
Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins
SeungHeeHa, HyoungKyuKim, NguyenThiTuyetAnh, NariKim, KyungSooKo, ByoungDooRhee, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 8 531-546 (16 pages)
Activation of Toll-like receptor-4 (TLR-4) in articular chondrocytes increases the catabolic compartment and leads to matrix degradation during the development of osteoarthritis. In this study, we determined the proteomic and genomic alterations in human chondrocytes during lipopolysaccharide (LPS)-induced inflammation to elucidate the underlying mechanisms and consequences of TLR-4 activation. Human chondrocytes were cultured with LPS for 12, 24,and 36 h to induce TLR-4 activation. The... -
NecroX-5 protects mitochondrial oxidative phosphorylation capacity and preserves PGC1α expression levels during hypoxia/ reoxygenation injury
VuThiThu, HyoungKyuKim, LeThanhLong, BayalagmaaNyamaa, In-SungSong, ToThanhThuy, NguyenQuangHuy, JubertMarquez, SoonHaKim, NariKim, KyungS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.2 9 201-211 (11 pages)
Although the antioxidant and cardioprotective effects of NecroX-5 on various in vitro and in vivo models have been demonstrated, the action of this compound on the mitochondrial oxidative phosphorylation system remains unclear. Here we verify the role of NecroX-5 in protecting mitochondrial oxidative phosphorylation capacity during hypoxia-reoxygenation (HR). Necrox-5 treatment (10 μM) and non-treatment were employed on isolated rat hearts during hypoxia/ reoxygenation treatment using an ex... -
Necrotrophic Fungus Pyrenophora tritici-repentis Triggers Expression of Multiple Resistance Components in Resistant and Susceptible Wheat Cultivars
Ethan J. Andersen, Madhav P. Nepal, Shaukat Ali 한국식물병리학회 The Plant Pathology Journal 16 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 2호 2 99-114 (16 pages)
Tan spot of wheat, caused by Pyrenophora tritici-re- pentis (Ptr), results in a yield loss through chlorosis and necrosis of healthy leaf tissue. The major objective of this study was to compare gene expression in resistant and susceptible wheat cultivars after infection with Ptr ToxA-producing race 2 and direct infiltration with Ptr ToxA proteins. Greenhouse experiments included ex- posure of the wheat cultivars to pathogen inoculum or direct infiltration of leaf tissue with Ptr-ToxA protein... -
siRNAs Derived from Cymbidium Mosaic Virus and Odontoglossum Ringspot Virus Down-modulated the Expression Levels of Endogenous Genes in Phalaenopsis equestris
Han-hong Lan, Cui-mei Wang, Shuang-shuang Chen, Jian-ying Zheng 한국식물병리학회 The Plant Pathology Journal 13 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 5호 11 508-520 (13 pages)
Interplay between Cymbidium mosaic virus (CymMV)/ Odontoglossum ringspot virus (ORSV) and its host plant Phalaenopsis equestris remain largely unknown, which led to deficiency of effective measures to control disease of P. equestris caused by infecting viruses. In this study, for the first time, we characterized viral small interfering RNAs (vsiRNAs) profiles in P. equestris co-infected with CymMV and ORSV through small RNA sequencing technology. CymMV and ORSV small interfering RNAs (siRNAs)... -
Genome-Wide Analysis of Type VI System Clusters and Effectors in Burkholderia Species
한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 1호 2 11-22 (12 pages)
Type VI secretion system (T6SS) has been discovered in a variety of gram-negative bacteria as a versatile weapon to stimulate the killing of eukaryotic cells or prokaryotic competitors. Type VI secretion effectors (T6SEs) are well known as key virulence factors for important pathogenic bacteria. In many Burkholderia species, T6SS has evolved as the most complicated secretion pathway with distinguished types to translocate diverse T6SEs, suggesting their essential roles in this genus. Here we... -
Characterization of the Rosellinia necatrix Transcriptome and Genes Related to Pathogenesis by Single-Molecule mRNA Sequencing
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 4호 2 362-369 (8 pages)
White root rot disease, caused by the pathogen Rosellinia necatrix, is one of the world’s most devastating plant fungal diseases and affects several commercially important species of fruit trees and crops. Recent global outbreaks of R. necatrix and advances in molecular techniques have both increased interest in this pathogen. However, the lack of information regarding the genomic structure and transcriptome of R. necatrix has been a barrier to the progress of functional genomic research... -
Profiling of Disease-Related Metabolites in Grapevine Internode Tissues Infected with Agrobacterium vitis
한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2016, 32권 6호 1 489-499 (11 pages)
Green shoot cuttings of 10 different grapevine species were inoculated with Agrobacterium vitis to find disease-related metabolites in the grapevine. Crown galls formed 60 days after inoculation varied in gall severity (GS) evaluated by gall incidence (GI) and gall diameter (GD), which were classified into three response types as RR (low GI and small GD), SR (high GI and small GD), and SS (high GI and large GD), corresponding to resistant, moderately resistant, and susceptible responses,... -
The Effects of Joint Reference and Mutual Exclusivity on the Application of Whole-Object Assumption in 3-Year Olds Filipino-English Bilingual Preschool Students
Edna S. Miraflores, Rochelle Irene G. Lucas 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 19 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2015, Vol.9 No.1 5 91-109 (19 pages)
This study investigated the word learning constraints 3-year old pre-school students resort to in learning a new word or label. The study tested three possible constraints specifically, the Whole Object Assumption to determine if it plays a primary role in the learning of a new word/label in young children, the Mutual Exclusivity Principle and the Joint Reference Principle to determine if these override the Whole Object Assumption in word learning. Each constraint was tested through audio-visual... -
Designing Researcher Information Retrieval Interface based on Ontological Analysis
서은경, 박미향, Seo. Eun-Gyoung, Park. Mi-Hyang 한국정보관리학회 정보관리학회지 22 Pages
한국정보관리학회 정보관리학회지 2009, Vol.26 No.2 173-194 (22 pages)
최근 특정 도메인의 개념에 대한 정확한 정의, 계층적 관계나 추론규칙을 정형화된 어휘로 기술된 온톨로지 지식을 기반하는 시맨틱 탐색기법이 정보검색시스템에 응용됨에 따라 이용자는 보다 쉽게 지식기반을 항해할 수 있다. 본 연구의 목적은 의미적 애매성을 줄여주고, 의미적 관계성을 제시해 줌으로서 이용자가 보다 정확하고 쉽게 정보를 검색할 수 있게 해주는 온톨로지 기반의 정보검색 인터페이스를 개발하는 것이다. 이를 위해서 본 연구는 연구자정보 기술요소들의 클래스의 계층관계, 데이터의 계층관계 및 속성, 관계... -
Proteomic Changes in the Sound Vibration-Treated Arabidopsis thaliana Facilitates Defense Response during Botrytis cinerea Infection
Ritesh Ghosh, Bosung Choi, Young Sang Kwon, Tufail Bashir, Dong-Won Bae, Hanhong Bae 한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 6호 7 609-622 (14 pages)
Sound vibration (SV) treatment can trigger various molecular and physiological changes in plants. Previously, we showed that pre-exposure of Arabidopsis plants to SV boosts its defense response against Botrytis cinerea fungus. The present study was aimed to investigate the changes in the proteome states in the SV-treated Arabidopsis during disease progression. Proteomics analysis identified several upregulated proteins in the SVinfected plants (i.e., SV-treated plants carrying Botrytis... -
Microarray Analysis of Gene Expression Profiles in Response to Treatment with Melatonin in Lipopolysaccharide Activated RAW 264.7 Cells
JuYeonBan, BumSikKim, SooCheolKim, DongHwanKim, Joo-HoChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.1 4 23-30 (8 pages)
Melatonin, which is the main product of the pineal gland, has well documented antioxidant and immune-modulatory effects. Macrophages produce molecules that are known to play roles in inflammatory responses. We conducted microarray analysis to evaluate the global gene expression profiles in response to treatment with melatonin in lipopolysaccharide (LPS) activated RAW 264.7 macrophage cells. In addition, eight genes were subjected to real-time reverse transcription polymerase chain reaction... -
고도화된 인간행동 시뮬레이션을 위한 건축정보 기반 온톨로지 활용기술 개발에 관한 연구
유정현(Jeong-Hyun Yu), 이윤길(Yun-Gil Lee) 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 8 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2018, 제 8권 제 10호 38 397-404 (8 pages)
본 연구는 보다 지능적인 인간행동 시뮬레이션 기술을 개발하기 위하여 진행되었다. 이를 위하여 본 연구에서는 온톨로지와 이의 추론을 통한 기술을 가상공간에 적용하는 방식을 사용하였다. 또한 이와 같은 기술이 설계과정과 보다 유기적으로 연계되어 활용될 수 있도록 하기위하여 상용 설계저작도구를 활용하였다. 즉, BIM(Building Information Modeling) 저작도구로부터 생성된 건물 모델에서 필요한 건축정보를 추출하고 이를 온톨로지 형태(OWL)의 파일로 전환하고 사람형상의 에이전트(Agent)를 기반으로 하는 가상공간에... -
인체자원은행의 효율적인 운영을 위한 OWL 기반의 데이터베이스 구축에 관한 연구
이상민, 김화선, 조훈 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 10 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2015, 제 5권 제 3호 7 55-64 (10 pages)
본 연구에서는 인체자원은행의 효율적인 운영과 인체자원은행간의 상호호환을 위해 온톨로지 기반 의 데이터베이스를 구축하였다. 본 연구팀은 선행연구에서 7,197,252개의 인체자원정보를 수집하여 고 품질 인체자원정보 데이터베이스를 구축하였다. 이 과정에서 1,796개의 임상항목을 분류하고 명확한 용어표현을 위해 국제표준용어체계인 SNOMED-CT와 매핑하였다. 그 결과 동일한 국제표준코드에 대 해 서로 다른 용어 및 값 유형, 자료 형을 가지는 826개의 유의어를 발견하였다. 본 연구에서는 유의 어로 인한 중복을 최소화하기... -
문화재 정보의 온톨로지 기반 검색시스템
백승재, 천현재, 이홍철, Baek. Seung-Jae, Cheon. Hyeon-Jae, Lee. Hong-Chul 한국컴퓨터정보학회 韓國컴퓨터情報學會論文誌 8 Pages
한국컴퓨터정보학회 韓國컴퓨터情報學會論文誌 2005, Vol.10 No.3 229-236 (8 pages)
시맨틱 웹(Semantic Web)은 정보자원의 효율적 검색, 통합, 재사용을 가능하게 한다. 현재의 웹 환경에서 사용되고 있는 키워드 검색방법은 단순한 문자열 일치 방법으로 인하여 정확한 검색결과에 한계가 있다. 이에 본 연구에서는 전통적인 키워드 검색에서의 나타난 문제점들을 해결할 방안으로 의미적인 연관성을 통한 온톨로지(Ontology) 검색방법을 제안하여 더욱 정확한 검색결과를 유도해 본다. 국내 문화재를 중심으로 하여 OWL기반의 온톨로지를 구축하였고 질의, 검색 방법으로는 RDQL 질의어와 Jena API를 사용하였다. 이와... -
온톨로지 기반의 사용자 의도를 고려한 맞춤형 검색 서비스
김수경, 김건우, Kim. Sukyoung, Kim. Gunwoo 한국지능정보시스템학회 지능정보연구 15 Pages
한국지능정보시스템학회 지능정보연구 2012, Vol.18 No.4 129-143 (15 pages)
웹 기술의 급속한 발전은 기업들이 관리해야 하는 정보량의 폭발적인 증가를 초래하였다. 이와 더불어 보다 정확한 정보를 찾기 위한 검색 엔진 솔루션 시장의 규모도 더불어 크게 증가하였다. 하지만 대부분의 검색엔진들은 사용자의 검색 의도를 고려하지 않고 사용자가 입력한 특정 키워드를 포함하는 문서들을 반환하는 방법을 채택하고 있어, 실제 사용자가 원하는 정보를 찾는데 까지는 부가적인 시간과 노력이 요구된다. 본 연구에서는 이러한 문제를 해결 하기 위한 중요 기술인 적합성을 만족시키기 위해 재현율과 정확율을 높일... -
BEYOND YOUNG PEOPLE’S PRIVACY ONLINE: DATA LITERACY PROJECTS FOR CRITICAL DATA EDUCATION
Luci Pangrazio 경인교육대학교 교육연구원 The Journal of Education 21 Pages
경인교육대학교 교육연구원 The Journal of Education 2020, Vol.3 No.2 2 19-39 (21 pages)
This paper is based on a presentation given at the ‘Rethinking Literacy, Digital Competency and Media Education in the Age of Digital Platforms’ webinar hosted by Gyeongin National University in September 2020. In the paper, I explore the difficulties of implementing ‘critical data education’ programs in schools with children and young people. Reporting on three research projects with over 150 Australian students (aged 8-16 years), I explore the challenges and opportunities that arose. Each... -
Comparative proteomic analysis of proteins expression changes in the mammary tissue of cows infected with Escherichia coli mastitis
Xiao-wei Zhao, Yong-xin Yang, Dong-wei Huang, Guang-long Cheng, Hui-ling Zhao 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 2 253-263 (11 pages)
Cows infected with Escherichia (E.) coli usually experience severe clinical symptoms, including damage to mammary tissues, reduced milk yield, and altered milk composition. In order to investigate the host response to E. coli infection and discover novel markers for mastitis treatment, mammary tissue samples were collected from healthy cows and bovines with naturally occurring severe E. coli mastitis. Changes of mammary tissue proteins were examined using two-dimensional gel... -
Genome Wide Analysis of the Potato Soft Rot Pathogen Pectobacterium carotovorum Strain ICMP 5702 to Predict Novel Insights into Its Genetic Features
Tista Mallick, Rukmini Mishra, Sasmita Mohanty, Raj Kumar Joshi 한국식물병리학회 The Plant Pathology Journal 13 Pages
한국식물병리학회 The Plant Pathology Journal 2022, 38권 2호 4 102-114 (13 pages)
Pectobacterium carotovorum subsp. carotovorum (Pcc) is a gram-negative, broad host range bacterial pathogen which causes soft rot disease in potatoes as well as other vegetables worldwide. While Pectobacterium infection relies on the production of major cell wall degrading enzymes, other virulence factors and the mechanism of genetic adaptation of this pathogen is not yet clear. In the present study, we have performed an in-depth genome-wide characterization of Pcc strain ICMP5702 isolated from... -
Computational Identification and Comparative Analysis of Secreted and Transmembrane Proteins in Six Burkholderia Species
한국식물병리학회 The Plant Pathology Journal 15 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 2호 7 148-162 (15 pages)
As a step towards discovering novel pathogenesis-related proteins, we performed a genome scale computational identification and characterization of secreted and transmembrane (TM) proteins, which are mainly responsible for bacteria-host interactions and interactions with other bacteria, in the genomes of six representative Burkholderia species. The species comprised plant pathogens (B. glumae BGR1, B. gladioli BSR3), human pathogens (B. pseudomallei K96243, B. cepacia LO6), and plant-growth... -
Research Notes : Transcriptome Analysis of the Small Brown Planthopper, Laodelphax striatellus Carrying Rice stripe virus
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2013, 29권 3호 12 330-337 (8 pages)
Rice stripe virus (RSV), the type member of the genus Tenuivirus, transmits by the feeding behavior of small brown planthopper (SBPH), Laodelphax striatellus. To investigate the interactions between the virus and vector insect, total RNA was extracted from RSV-viruliferous SBPH (RVLS) and non-viruliferous SBPH (NVLS) adults to construct expressed sequence tag databases for comparative transcriptome analysis. Over 30 million bases were sequenced by 454 pyrosequencing to construct 1,538 and 953 of... -
대규모 산업시설에서 고장보고서로부터 고장지식 추출 프레임워크 개발
김도형(Dohyeong Kim), 강병호(Byeong Ho Kang), 이승룡(Sungyoung Lee) 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 10 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2018, 제 8권 제 3호 89 955-964 (10 pages)
대규모 산업시설은 고장 진단 및 조치는 현장 전문가에 의해 이루어진다. 하지만, 모든 고장을 한 정된 현장 전문가에 의존하는 것은 한계가 있다. 이러한 이유로 산업계에서는 고장보고서를 기록하여, 추후 고장 조치에 이용하고자 축적하고 있다. 하지만, 지식 재이용에 대한 접근이 없어 적합한 자료 를 적시에 획득하지 못하기 때문에 고장조치가 늦어지고 그로 인한 조업 지연으로 경제적 손실을 초 래하고 있다. 따라서 본 논문에서는 자연어로 작성된 고장보고서를 시스템이 이용할 수 있도록 정형 지식으로 자동으로 변환하고,... -
생태학적 “교사 행위주체성”의 한계와 대안: 비판적 실재론에 기반한 ‘관계적 교사행위자성’ 개념모델 탐색
한국교육사회학회 교육사회학연구 2021, 제 31권 제 1호 5 129-154 (26 pages)
본 연구는 실용주의에 기반한 ‘생태학적 관점의 교사 행위주체성 개념모델’(Priestly, Biesta & Robnison, 2015)의 특징과 한계를 비판적으로 논의하고, 이를 극복할 수 있는 대안으로 ‘비판적 실재론에 기반한 관계적 교사행위자성 개념모델’이 지향해야 할 방향과 주요 특징을 탐색적 차원에서 제안하는 데 목적을 둔다. 이를 위해 ‘형태발생론적 접근(Morphogenetic Approach)’(Archer, 1995)과 ‘비판적 실재론에 기반한 관계 사회학(Critical Realist Relational Sociology)’(Donati, 2011)을 이론적 틀로 활용했다. 분석...
