여성은 생리적 특성으로 인해 남성과 다른 또는 월경주기에 따른 반응의 차이가 존재할 수 있게 된다. 이전의 연구들이 월경주기에 따라 염증과 면역반응이 다르게 나타날 수가 있음을 보고하고 있으며, 현재까지 연구들이 진행되고 있지만 아직까지 명확한 결론의 도출이 이루어지지 못하고 있다. 따라서 월경주기에 따른 운동방법이나 강도가 여성의 염증반응과 면역기능에 어떠한 변화와 영향을 미치는가에 대한 의문이 지속적으로 제기되고 있다. 선행연구를 살펴볼 때 분명히 고강도 운동은 혈액 내의 염증반응을 일으키고, 면역기능에 변화를 일으킬 것으로 예측된다. 그러므로 여성들의 월경주기 중 황체기중반(mid-luteal phase: ML, 월경 전 6-9일)과 난포기중반(mid-follicular phase: MF, 월경 후 8-11일)에 30분간의 고강도 내리막 달리기가 혈중 염증반응 및 면역기능에 어떠한 영향을 미치는지 살펴볼 필요가 있을 것이다. 이 연구의 결과들은 월경주기에 따른 염증반응과 면역기능의 반응을 이해함으로써 이들에세 적절한 운동강도와 방법을 제시하는데 도움을 줄 수 있을 것으로 사료된다.
The purpose of this study was to investigate the physiological effects of exercise high-intensity down-hill running on immune function and inflammatory responses at mid-follicular phase(MF) and mid-luteal(ML) phase in eumenorrheic and healthy women in twenties. Subjects were random assigned was performed twice during about 120 min including resting 30 min, down-hill running 30 min, recovery 1h during two different phases of the menstrual cycle: MF (8-11 days after menstruation) and ML(6-9 days before menstruation). females completed 30 min down-hill running by–17.6% at 70% of maximal oxygen consumption (VO2max) after resting and Tympanic temperature, Heart Rate(HR), Rating of Perceived Exertion(RPE), Delayed onset muscle soreness(DOMS) during test. Blood samples were assessed pre-exercise, immediately post-exercise, 24 h post-exercise, Complete blood cell count (CBC), CK, LDH, CRP, IgG, Cortisol was measured. Condition x time interaction were analyzed by repeated measure ANOVA, There was a significantly different between condition on change in RPE (p<.05) and change in WBC, CRP concentrations in interaction (p<.05). The result of this study indicate that women perceived exercise-intensity in MLl more than MF, WBC that appeared all high in ML indicates possibility that high-intensity exercise in ML may be induce increase of inflammatory reaction and muscle damage as high level of inflammatory markers. In addition, CRP levels were rapidly increased at Post-24h in ML, however, It was not level which can heighten the risk of cardiovascular disease because it was inside normal figure. Though women was attention to increase in muscle soreness and inflammation protein by inflammatory reaction when exercise in ML.
Ⅰ. 서 론 Ⅱ. 연구방법 Ⅲ. 연구결과 IV. 논 의 V. 결론 및 제언 참고문헌
